91202-39-0Relevant academic research and scientific papers
Solid-supported cross-metathesis and a formal alkane metathesis for the generation of biologically relevant molecules
Mndez, Luciana,Mata, Ernesto G.
, p. 81 - 86 (2015/08/18)
Solid-phase synthetic strategies toward the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium-catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages.
Synthesis of 2-hydroxy-3,6,10-trimethylbenzocyclooct-5-ene (isoparvifolin), a sesquiterpenic benzocyclooctene
Sudalai, A.,Rao, G.S.Krishna
, p. 219 - 222 (2007/10/02)
The synthesis of 2-hydroxy-3,6,10-trimethylbenzocyclooct-5-ene (2) (isoparvifolin), a double bond isomer of the naturally occuring phenolic sesquiterpene (1) (parvifolin) is described.The key intermediate, 6-(3-methoxy-4-methylphenyl)heptanoic acid (3), required for the synthesis of 2 has been made from the keto ester (4) in two ways (4 -> 5 -> 6 -> 7 -> -> 3; 4-> -> 8 -> -> 3).The methoxyaryl heptanoic acid (3) is cyclodehydrated to the benzocyclooctanone (9).Vilsmeier reaction on the corresponding benzocyclooctanol, obtained by NaBH4 reduction of 9 gives the unsaturated aldehyde (10).Two functional group transformations on 10 (CHO -> CH3 and OCH3 -> OH) by standard procedures finally yield isoparvifolin (2).
Photochemistry and Photophysics of Surfactant trans-Stilbenes in Supported Multilayers and Films at the Air-Water Interface
Mooney, William F.,Brown, Patti E.,Russell, John C.,Costa, Silvia B.,Pedersen, Lee G.,Whitten, David G.
, p. 5659 - 5667 (2007/10/02)
The synthesis and study of several surfactant trans-stilbene derivatives are described.Both compounds containing the trans-stilbene at the hydrophobic terminal of a surfactant chain and those containing an intrachain stilbene chromophore have been studied
