912556-91-3

Basic information

• Product Name: Gefitinib InterMediate B
• Synonyms: Gefitinib InterMediate B;N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-Methoxyquinazolin-4-aMine
• CAS NO: 912556-91-3
• Molecular Formula: C₁₈H₁₆Cl₂FN₃O₂
• Molecular Weight: 396.25
• Mol File: 912556-91-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 234-236 °C
• Boiling Point: 523.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.392±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 5.40±0.30(Predicted)
• CAS DataBase Reference: Gefitinib InterMediate B(CAS DataBase Reference)
• NIST Chemistry Reference: Gefitinib InterMediate B(912556-91-3)
• EPA Substance Registry System: Gefitinib InterMediate B(912556-91-3)

Safety Data

• Hazardous Substances Data: 912556-91-3(Hazardous Substances Data)

Upstream product

• 367-21-5 3-chloro-4-fluorophenylamine 
• 52805-46-6 2-methoxy-5-cyanophenol 
• 1315512-62-9 5-(3-chloropropoxy)-4-methoxy-2-aminobenzonitrile 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 1315512-61-8 C₁₁H₁₁ClN₂O₄ 
• 929683-54-5 3-(3-chloropropoxy)-4-methoxybenzaldehyde 
• 621-59-0 isovanillin 
• 179688-52-9 6-hydroxy-7-methoxyquinazolin-4(3H)-one 
• 13794-72-4 3H-6,7-dimethoxyquinazolin-4-one 
• 109-70-6 1.3-chlorobromopropane 
• 184475-71-6 4-(3-chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline 
• 788136-89-0 4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate 
• 230955-75-6 6-acetoxy-4-chloro-7-methoxyquinazoline 
• 179688-53-0 6-acetoxy-7-methoxy-3,4-dihydroquinazolin-4-one 

Downstream Products

• 184475-35-2 gefitinib 
• 1259017-48-5 3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)propyl 4-methylpiperazine-1-carbodithioate 
• 1438080-43-3 tert-butyl 5-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate 
• 1438080-49-9 tert-butyl 1-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)hexahydropyrrolo[3.4-b]pyrrole-5(1H)carboxylate 
• 1438075-52-5 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-methylhexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl) propoxy)quinazolin-4-amine 
• 295330-38-0 tert-butyl 4-[3-[4-(3-chloro-4-fluoro-anilino)-7-methoxy-quinazolin-6-yl]oxypropyl]piperazine-1-carboxylate 
• 1438073-26-7 N-(3-chloro-4-fluorophenyl)-6-(3-(hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)propoxy)-7-methoxyquinazolin-4-amine 
• 1438082-56-4 tert-butyl 6-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)octahydro-1H-pyrrolo[3,4-b] pyridine-1-carboxylate 
• 1445860-68-3 4-(3'-chloro-4'-fluorophenylamino)-6-[3-(2-oxa-6-azaspiro[3.4]octane-6-yl)propoxy]-7-methoxyquinazoline 
• 1456070-18-0 C₂₂H₂₄ClFN₄O₃ 
• 1456070-17-9 C₂₁H₂₂ClFN₄O₃ 
• 1456070-16-8 C₂₃H₂₄ClFN₄O₄S 
• 1438075-40-1 N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(tetrahydro-2H-[1,4]dioxino[2,3-c]pyrrol-6(3H)-yl)propoxy)quinazolin-4-amine 
• 1438072-05-9 N-(3-chloro-4-fluorophenyl)-6-(3-(5.6-dihydro-[1,2,4]triazolo[4.3-a]pyrazin-7(8H)-yl)propoxy)-7-methoxyquinazolin-4-amine 

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