91375-39-2Relevant academic research and scientific papers
USES OF Si-N BONDS IN ORGANIC SYNTHESIS. A DIRECT SYNTHESIS OF FUNCTIONAL PROTECTED PROPARGYLIC PRIMARY AMINES.
Corriu, Robert J. P.,Huynh, Vilam,Moreau, Joel J. E.
, p. 1887 - 1890 (1984)
An easy route to lithium N,N-bis(trimethylsilyl)aminomethylacetylide 1 is described.Reactions of 1 with electrophiles give rise to various protected primary amines.
Silylamines in Organic Synthesis. Facile Synthetic Routes to Unsaturated Protected Primary Amines.
Corriu, Robert J. P.,Huynh, Vilam,Iqbal, Javed,Moreau, Joel J. E.,Vernhet, Claude
, p. 6231 - 6244 (2007/10/02)
The reactions of lithium N,N-bis(trimethylsilyl)aminomethyl acetylide with electrophilic reagents offered a short preparation of substituted and functional propargyl amines.These are shown to be useful precursors of various saturated protected primary amines.Addition reactions to the carbon-carbon triple bond or isomerisation reactions gave rise to allylic, dienic and α-allenic amines. Keywords: Silylamines; propargylamines, α-allenylamines; N,N-bis(silyl)dienamines.
