913836-17-6

Basic information

• Product Name: 5-BROMO-4-METHOXYCARBONYL-2(1H)-PYRIDINONE
• Synonyms: METHYL 5-BROMO-2-HYDROXY-4-PYRIDINECARBOXYLATE;METHYL 5-BROMO-2-HYDROXYISONICOTINATE;Methyl 5-Bromo-2-hydroxypyridine-4-carboxylate, 5-Bromo-4-methoxycarbonyl-2(1H)-pyridinone;Methyl 5-bromo-2-hydroxyisonicotinate 98%;4-Pyridinecarboxylic acid, 5-broMo-1,2-dihydro-2-oxo-, Methyl ester;Methyl 5-broMo-2-hydroxypyridine-4-carboxylate;Methyl 5-broMo-2-oxo-1,2-dihydropyridine-4-carboxylate;Methyl 5-bromo-2-hydroxypyridine-4-carboxylate, 5-Bromo-2-hydroxy-4-(methoxycarbonyl)pyridine
• CAS NO: 913836-17-6
• Molecular Formula: C₇H₆BrNO₃
• Molecular Weight: 232.03144
• Product Categories: blocks;Pyridines
• Mol File: 913836-17-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 400.9 °C at 760 mmHg
• Flash Point: 196.3 °C
• Appearance: /
• Density: 1.716 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 8.96±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-4-METHOXYCARBONYL-2(1H)-PYRIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-4-METHOXYCARBONYL-2(1H)-PYRIDINONE(913836-17-6)
• EPA Substance Registry System: 5-BROMO-4-METHOXYCARBONYL-2(1H)-PYRIDINONE(913836-17-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 913836-17-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-4-methoxycarbonyl-2(1H)-pyridinone, also known as BMPCP, is a chemical compound with the molecular formula C7H6BrNO3. 5-BROMO-4-METHOXYCARBONYL-2(1H)-PYRIDINONE is a derivative of pyridine and is commonly used as a building block in organic synthesis. It is known for its strong inhibitory effect on the enzyme phenylalanine ammonia lyase, making it a potential candidate for pharmaceutical research. BMPCP has also been studied for its antiproliferative and anti-inflammatory properties. It is important to note that BMPCP is considered a hazardous chemical and should be handled with care, as it can irritate the skin, eyes, and respiratory system.

Upstream product

• 882499-87-8 methyl 2-amino-5-bromo-pyridine-4-carboxylate 
• 13472-85-0 2-methoxy-5-bromopyridine 
• 886365-25-9 methyl 5-bromo-2-methoxy-pyridine-4-carboxylate 
• 886365-22-6 5-bromo-2-methoxypyridine-4-carboxylic acid 
• 936011-17-5 5-bromo-2-methoxy-pyridine-4-carbaldehyde 
• 67-56-1 methanol 
• 913836-16-5 C₆H₄BrNO₃ 

Downstream Products

• 1590407-03-6 C₁₉H₁₀F₄N₂O₂ 
• 1590403-91-0 C₂₆H₁₈F₄N₂O₃ 
• 1590403-90-9 C₁₉H₁₁F₄NO₄ 
• 1590411-04-3 C₁₉H₁₂F₄N₂O₃ 
• 1590411-03-2 C₂₀H₁₃F₄NO₄ 
• 1578246-57-7 7-(benzyloxy)-N-cyclohexyl-2,6-naphthyridin-1-amine 
• 1578246-54-4 7-(benzyloxy)-1-(1-methyl-1H-pyrazol-4-yl)-2,6-naphthyridine 
• 1578246-53-3 7-(benzyloxy)-2,6-naphthyridin-1-yl trifluoromethanesulfonate 
• 1578246-52-2 7-(benzyloxy)-2,6-naphthyridin-1-ol 
• 1578246-51-1 (E)-methyl 2-(benzyloxy)-5-(2-ethoxyvinyl)isonicotinate 
• 1578244-65-1 N-(4-(1,2-dimethyl-1H-imidazol-5-yl)-2-methoxyphenyl)-5-(1-methyl-1H-pyrazol-4-yl)-2,6-naphthyridin-3-amine 
• 1578244-64-0 N-(2-methoxy-4-(1-methyl-1H-pyrazol-4-yl)phenyl)-5-(1-methyl-1H-pyrazol-4-yl)-2,6-naphthyridin-3-amine 
• 1222090-62-1 methyl 2-(benzyloxy)-5-bromoisonicotinate 

Relevant articles and documents

TRICYCLIC FUSED DERIVATIVES OF 1-(CYCLO)ALKYL PYRIDIN-2-ONE USEFUL FOR THE TREATMENT OF CANCER

The present disclosure described heterocyclic compounds of Formula I or, its stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms and pharmaceutically active derivative thereof and pharmaceutical compositions containing them as the active ingredient. The present disclosure also describes the synthesis and characterization of aforementioned compounds to exhibit high anticancer activity. The compounds of the present disclosure are useful as medicaments and their use in the manufacture of medicaments for treatment, prevention or suppression of diseases, and conditions mediated by one or more BET family of bromodomains.

ANTI-FIBROTIC PYRIDINONES

Disclosed are pyridinone compounds, method for preparing these compounds, and methods for treating fibrotic disorders.