914943-46-7

Upstream product

• 914942-96-4 7-[3-(aminomethyl)phenyl]-1,6-dihydro-N,1-dimethyl-imidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-(t-butyloxycarbonylamine) 
• 3282-30-2 pivaloyl chloride 
• 190771-22-3 3-((trimethylsilyl)ethynyl)benzonitrile 
• 171290-53-2 3-ethynylbenzonitrile 
• 26820-38-2 (3,5-dinitropyridin-4-yl)methylamine 
• 10425-70-4 4-chloro-3,5-dinitropyridine 
• 69113-59-3 3-iodobenzonitrile 
• 19872-96-9 1H-3,5-dinitropyridine-4-one 
• 914942-92-0 tert-butyl 6-amino-7-(2-(3-cyanophenyl)ethynyl)-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl(methyl)carbamate 
• 914942-93-1 3-[1,6-dihydro-1-methyl-4-(N-tert-butyloxycarbonyl-N-methylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]benzonitrile 
• 914942-87-3 tert-butyl 6-(diphenylmethyleneamino)-1-methyl-1H-imidazo[4,5-c]pyridine-4-yl(methyl)carbamate 
• 914942-88-4 tert-butyl (6-amino-7-iodo-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)(methyl)carbamate 
• 914942-86-2 2,6-dichloro-4-N-methylpyridine-3,4-diamine 
• 914942-85-1 2,6-dichloro-N-methyl-N-nitro pyridine-4-amine 

Relevant academic research and scientific papers

1, 6 -DIHYDRO- 1,3, 5, 6-TETRAAZA-AS-INDACENE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AS INHIBITORS OF IKK ENZYME ACTIVITY

The present invention provides for tricyclic compounds having the formula (I) wherein R1, R2, R5, R6, R7, and R8 are as described herein. The present invention further provides pharmaceutical compositions comprising such compounds, as well as the use of such compounds for treating inflammatory and immune diseases.