914942-93-1

Basic information

• Product Name: 3-[1,6-dihydro-1-methyl-4-(N-tert-butyloxycarbonyl-N-methylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]benzonitrile
• Synonyms: 3-[1,6-dihydro-1-methyl-4-(N-tert-butyloxycarbonyl-N-methylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]benzonitrile
• CAS NO: 914942-93-1
• Molecular Weight: 402.456
• Mol File: 914942-93-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-[1,6-dihydro-1-methyl-4-(N-tert-butyloxycarbonyl-N-methylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[1,6-dihydro-1-methyl-4-(N-tert-butyloxycarbonyl-N-methylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]benzonitrile(914942-93-1)
• EPA Substance Registry System: 3-[1,6-dihydro-1-methyl-4-(N-tert-butyloxycarbonyl-N-methylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]benzonitrile(914942-93-1)

Safety Data

• Hazardous Substances Data: 914942-93-1(Hazardous Substances Data)

Upstream product

• 190771-22-3 3-((trimethylsilyl)ethynyl)benzonitrile 
• 171290-53-2 3-ethynylbenzonitrile 
• 26820-38-2 (3,5-dinitropyridin-4-yl)methylamine 
• 10425-70-4 4-chloro-3,5-dinitropyridine 
• 69113-59-3 3-iodobenzonitrile 
• 19872-96-9 1H-3,5-dinitropyridine-4-one 
• 914942-87-3 tert-butyl 6-(diphenylmethyleneamino)-1-methyl-1H-imidazo[4,5-c]pyridine-4-yl(methyl)carbamate 
• 914942-88-4 tert-butyl (6-amino-7-iodo-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl)(methyl)carbamate 
• 914942-86-2 2,6-dichloro-4-N-methylpyridine-3,4-diamine 
• 914942-85-1 2,6-dichloro-N-methyl-N-nitro pyridine-4-amine 
• 887147-25-3 tert-butyl 6-amino-1-methyl-1H-imidazo[4,5-c]pyridin-4-yl(methyl)carbamate 
• 887147-22-0 4-[N-(methyl)-N-(tert-butyloxycarbonyl)amino]-6-chloro-1-methyl-1H-imidazo[4,5-c]pyridine 
• 887147-20-8 2,6-dichloro-N-methyl-3-nitro pyridine-4-amine 
• 887147-21-9 4-methylamino-6-chloro-1-methyl-1H-imidazo[4,5-c]pyridine 

Downstream Products

• 914942-96-4 7-[3-(aminomethyl)phenyl]-1,6-dihydro-N,1-dimethyl-imidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-(t-butyloxycarbonylamine) 
• 914942-98-6 N-[[3-[1,6-dihydro-1-methyl-4-(methyl-t-butyloxycarbonylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]phenyl]methyl]acetamide 
• 914943-46-7 N-[[3-[1,5-dihydro-1-methyl-4-(methyl-t-butyloxycarbonylamino)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-7-yl]phenyl]methyl]trimethylacetamide 

Relevant articles and documents

Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IκB kinase

A new series of tricyclic-based inhibitors of IKK have been derived from an earlier lead compound. The synthesis and structure-activity relationships (SAR) are described. Compound 4k inhibited TNF production in rats stimulated with LPS.