92115-31-6

Upstream product

• 92115-33-8 r-3-hydroxy-2,2,c-4-trimethyl-3-phenylcyclobutanone 
• 92115-33-8 r-3-hydroxy-2,2,t-4-trimethyl-3-phenylcyclobutanone 
• 98-86-2 acetophenone 
• 93-89-0 benzoic acid ethyl ester 
• 13988-65-3 4-methyl-1-phenyl-pentane-1,3-dione 
• 74-88-4 methyl iodide 
• 563-80-4 3-methyl-butan-2-one 

Downstream Products

• 92115-33-8 r-3-hydroxy-2,2,c-4-trimethyl-3-phenylcyclobutanone 
• 93-55-0 1-phenyl-propan-1-one 
• 103595-95-5 2,2,4-trimethyl-5-phenylfuran-3(2H)-one 
• 65-85-0 benzoic acid 
• 122756-90-5 4-hydroxy-3,5,5-trimethyl-4-phenyl-4,5-dihydrofuran-2(3H)-one 
• 103595-96-6 6-hydroxy-3,3,5-trimethyl-6-phenyl-1,2-dioxan-4-one 
• 16424-63-8 2,2,4-trimethyl-1-phenylpentane-1,3-dione 
• 344558-83-4 2,4-dimethyl-1-phenyl-1,3-pentanedione-4-d₁ 
• 154461-63-9 (1R,2S)-1-hydroxy-2,4-dimethyl-1-phenyl-3-pentanone 

Relevant academic research and scientific papers

Enantioselective borohydride reduction catalyzed by optically active cobalt complexes

The highly enantioselective borohydride reduction of aromatic ketones or imines to the corresponding alcohols was developed in the presence of a catalytic amount of an optically active cobalt(II) complex catalyst. This enantioselective reduction is carried out using a precisely premodified borohydride with alcohols such as tetrahydrofurfuryl alcohol, ethanol and methanol. High optical yields are obtained by choosing the appropriate alcohol as modifiers and a suitable β-ketoiminato ligand of the catalyst. The enantioselective borohydride reduction has been successfully applied to the preparation of optically active 1,3-diols, the stereoselective reduction of diacylferrocenes, and dynamic and/or kinetic resolution of 1,3-dicarbonyl compounds.

Clemmensen Reduction. X. The Synthesis and Acidolysis of Some Aryl Alkyl Substituted Cyclopropane-1,2-diols

The synthesis of a number of 1-alkyl-2-arylcyclopropane-1,2-diols is reported.Reductive treatment of suitably substituted 1,3-diketones gave a cyclopropanediyl diacetate from which the diol was obtained.Reaction of these diols with acid gave α-hydroxy ketones, in which an alkyl group, rather than an aryl group, was adjacent to the carbonyl function.Clemmensen reduction of the 1,3-diketones gave products of rearrangement, generally similar to those obtained by acidolysis of the cyclopropane-1,2-diols.The relationship of these results to thermochemical studies on the stability of carboxonium ions is discussed.

PHOTOCHEMICAL REACTION OF PHENYL-SUBSTITUTED 1,3-DIKETONES.

Irradiation of 2,2-dimethyl-1-phenyl-1,3-diketones with 3-ethyl or 3-isopropyl substituents gave type II cyclization product, 3-hydroxy-2,2,4-trimethyl-3-phenylcyclobutanone or 3-hydroxy-2,2,4,4-tetramethyl-3-phenylcyclobutanone, along with type I cleavage products. The type II cyclization/type I cleavage ratio is greater with a 3-isopropyl group than with a 3-ethyl group. A similar irradiation of 2,2-dimethyl-1-phenyl-1,3-butanedione gave type I cleavage products and no type II cyclization product. Irradiation of 2,4-dimethyl-1-phenyl-1,3-pentanedione gave 3-hydroxy-2,2,4-trimethyl-3-phenylcyclobutanone and propiophenone.