92367-55-0

Basic information

• Product Name: 4-(4-hydroxybutyl)benzonitrile
• Synonyms: 4-(4-hydroxybutyl)benzonitrile
• CAS NO: 92367-55-0
• Molecular Weight: 175.23
• Mol File: 92367-55-0.mol

Chemical Properties

• CAS DataBase Reference: 4-(4-hydroxybutyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-hydroxybutyl)benzonitrile(92367-55-0)
• EPA Substance Registry System: 4-(4-hydroxybutyl)benzonitrile(92367-55-0)

Safety Data

• Hazardous Substances Data: 92367-55-0(Hazardous Substances Data)

Upstream product

• 150465-56-8 4-(p-cyanophenyl)-3-buten-1-ol 
• 623-00-7 4-bromobenzenecarbonitrile 
• 15451-33-9 4-(but-3-en-1-yl)benzonitrile 
• 623-03-0 4-Cyanochlorobenzene 
• 627-27-0 homoalylic alcohol 

Downstream Products

• 31419-48-4 4-(p-cyanophenyl)butanoic acid 
• 1219041-08-3 4-(4-cyanophenyl)butyl methanesulfonate 

Relevant articles and documents

Radical Chain Reduction via Carbon Dioxide Radical Anion (CO2?-)

We developed an effective method for reductive radical formation that utilizes the radical anion of carbon dioxide (CO2?-) as a powerful single electron reductant. Through a polarity matched hydrogen atom transfer (HAT) between an electrophilic radical and a formate salt, CO2?- formation occurs as a key element in a new radical chain reaction. Here, radical chain initiation can be performed through photochemical or thermal means, and we illustrate the ability of this approach to accomplish reductive activation of a range of substrate classes. Specifically, we employed this strategy in the intermolecular hydroarylation of unactivated alkenes with (hetero)aryl chlorides/bromides, radical deamination of arylammonium salts, aliphatic ketyl radical formation, and sulfonamide cleavage. We show that the reactivity of CO2?- with electron-poor olefins results in either single electron reduction or alkene hydrocarboxylation, where substrate reduction potentials can be utilized to predict reaction outcome.

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