92554-86-4

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 5351-17-7 4-aminobenzohydrazide 
• 94-09-7 p-aminoethylbenzoate 
• 619-45-4 4-methoxycarbonyl aniline 
• 150-13-0 4-amino-benzoic acid 
• 904633-64-3 C₁₅H₁₅N₃O₃ 
• 3290-99-1 4-methoxybenzoic acid hydrazide 
• 122-04-3 4-nitro-benzoyl chloride 
• 92555-33-4 1-(4-methoxybenzoyl)-2-(4-nitrobenzoyl)hydrazine 
• 62507-51-1 2-(4-methoxyphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole 

Downstream Products

• 1244549-64-1 2-[2-[(2,6-dichlorophenyl)amino]benzyl]-3-[4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]phenyl]quinazolin-4(3H)-one 
• 1244549-79-8 2-[2-[(2,6-dichlorophenyl)amino]benzyl]-3-[4-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]phenyl]-6-bromoquinazolin-4(3H)-one 
• 1333868-34-0 4-(2-(4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)phenylamino)ethoxy)-2H-chromen-2-one 

Relevant academic research and scientific papers

17O NMR studies of substituted 1,3,4-oxadiazoles

Three series of substituted 1,3,4-oxadiazoles were studied by 17O NMR spectroscopy. Chemical shifts values were correlated with empirical Hammett parameters as well as calculated bond lengths and chemical shielding values.

Synthesis and biological evaluation of 1,3,4-oxadiazole derivatives as novel analgesic and antiinflammatory agents

A novel series of 4-(2-(4-(5-(4-substituted phenyl)-1,3,4-oxadiazol-2-yl) phenylamino)ethoxy)-2H-chromen-2-one (7a-j) have been synthesized from 4-(5-(4-substituted phenyl)-1,3,4-oxadiazol-2-yl)benzenamine (4a-j) and 4-(2-bromoethoxy)-2H-chromen-2-one (5). The synthesized compounds were characterized on the basis of their spectral (IR, 1H NMR) data and evaluated for the anti-inflammatory and analgesic activity by using different pharmacological models. The most active compounds were subjected to acute ulcerogenesis activity and were found to be less ulcerogenic than the standard.

Synthesis and antimicrobial activity of novel 1,3,4-oxadiazolyl-quinazolin- 4(3H)ones

A series of 1,3,4-oxadiazolyl-quinazolin-4(3H)ones have been synthesized using known methods. All the compounds have been established on basis of elemental analysis, IR and NMR spectral data. The in vitro antimicrobial screening of the synthesized compounds were carried out against two gram-positive bacteria (S. aureus, S. pyogenes), two gram-negative bacteria (E. coli, P. aeruginosa), and three fungal species (C. albicans, A. niger, A. clavatus) using the broth microdilution method. The compounds 7d, 7g, 7l, 7o, 7p, and 7r possessed pronounced antibacterial activity whereas compound 7p exhibited promising antifungal activity.

Synthesis, anti-HIV, and antifungal activity of new benzensulfonamides bearing the 2,5-disubstituted-1,3,4-oxadiazole moiety

A series of novel chiral and achiral N-[1-(1,3,4-oxadiazol-2ylthio)alkyl]- 4-methyl/chloro/methoxybenzenesulfonamides 5a-l were prepared by the reaction of 4-(4-methyl, chloro, methoxyphenylsulfonamido)alkyl carboxylic acid hydrazides 4a-l with CS2 and KO