927-60-6

Basic information

• Product Name: 4-hydroxybutyramide
• Synonyms: 4-hydroxybutyramide;4-Hydroxybutanamide;.gamma.-Hydroxybutyramide;4-Hydroxybutryamide;4-Hydroxybutyric acid amide;Butanamide, 4-hydroxy-;Butyramide, 4-hydroxy-;Hydroxybutyramide
• CAS NO: 927-60-6
• Molecular Formula: C₄H₉NO₂
• Molecular Weight: 103.11976
• EINECS: 213-155-6
• Mol File: 927-60-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 354.1°C at 760 mmHg
• Flash Point: 167.9°C
• Appearance: /
• Density: 1.11g/cm³
• Vapor Pressure: 1.98E-06mmHg at 25°C
• Refractive Index: 1.465
• CAS DataBase Reference: 4-hydroxybutyramide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxybutyramide(927-60-6)
• EPA Substance Registry System: 4-hydroxybutyramide(927-60-6)

Safety Data

• Hazardous Substances Data: 927-60-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 206, 1968 DOI: 10.1021/jo01265a039

InChI:InChI=1/C4H9NO2/c5-4(7)2-1-3-6/h6H,1-3H2,(H2,5,7)

Upstream product

• 123-56-8 Succinimide 
• 96-48-0 4-butanolide 
• 628-22-8 4-hydroxy-1-butanitrile 
• 100446-67-1 4-trimethylsiloxybutyramide 
• 925-57-5 methyl 4-hydroxybutanoate 

Downstream Products

• 123-56-8 Succinimide 
• 628-20-6 4-Chlorobutyronitrile 

Relevant articles and documents

A mild and facile synthesis of cyclic imides using pyridinium chlorochromate

A mild and facile synthetic method of cyclic imides is presented. These compounds are widely used in the synthesis of novel medical, polymeric, photonic and electronic materials. Compared with traditional syntheses, the method reported has several advantages including mild conditions, simplified work-up and low cost.

A mild hydration of nitriles into amides

Stirring mixtures of β-hydroxynitriles with manganese dioxide, deposited onto silica gel for a few days at room temperature resulted in the formation of the corresponding amides in fair to good yields. The unprecedented conversion of 3-hydroxyglutarodinitrile into the corresponding monoamide has been performed by this methodology.