251571-56-9

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 196861-59-3 (R)-1,2,4-Tris-trimethylsilanyloxy-butane 
• 42890-76-6 (S)-1,2,4-butanetriol 

Downstream Products

• 935475-92-6 (3S)-3-[(4-methoxybenzyl)oxy]-4-pentenoic acid 
• 1242065-84-4 (1R)-1,2-anhydro-3,5-dideoxy-1-ethenyl-4-O-{(3S)-3-[ (4-methoxybenzyl)oxy]pent-4-enoyl}-D-threopentitol 
• 1242065-83-3 (1aS,3R,7S,9aR)-7-[(4-methoxybenzyl)oxy]-3-methyl-2,3,5,6,7,9a-hexahydro-1aH-oxireno[2,3-d]oxecin-5-one 
• 276248-87-4 (R)-1-Methoxy-4-(4-methoxy-benzyloxy)-butan-2-ol 
• 290835-89-1 (E)-(S)-3-(4-Methoxy-benzyloxy)-hepta-4,6-dienoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 369379-00-0 (Z,4S,5S)-5-(3-Hydroxypropenyl)-4-(4-methoxybenzyloxy)pyrrolidin-2-one 
• 290835-90-4 (E,3S)-N-Hydroxy-3-(4-methoxybenzyloxy)hepta-4,6-dienamide 
• 290835-88-0 (E)-(S)-3-(4-Methoxy-benzyloxy)-hepta-4,6-dienoic acid 
• 290835-91-5 (4aS,5S)-5-(4-Methoxybenzyloxy)-2,4a,5,6-tetrahydro-7H-pyrrolo[1,2-b]oxazin-7-one 
• 290835-87-9 (E,S)-3-(4-Methoxybenzyloxy)hepta-4,6-dien-1-ol 
• 290835-94-8 (1S,7aS)-1-(4-Methoxybenzyloxy)-1,2,5,7a-tetrahydro-3H-pyrrolizin-3-one 
• 369379-16-8 (E,S)-3-(4-Methoxybenzyloxy)hepta-4,6-dienal 
• 631416-69-8 (3S)-3-((methoxyphenyl)methyl)oxy-5-hydroxy-1-octen-7-yne 
• 631416-68-7 (3S)-3-((4-methoxyphenyl)methyl)oxy-5-formyl-1-pentene 

Relevant academic research and scientific papers

A method for preparation of a purine derivative and intermediates

The invention discloses a preparation method and intermediates of purine derivatives. According to the preparation method, a compound II and a compound III have a coupling reaction in an organic solvent under the actions of alkali and palladium catalysts to prepare the purine derivatives. Compared with the prior art, the raw materials used in the preparation method are cheap and common, and the preparation method is simple and efficient, is suitable for industrial production and provides a new way for the synthesis of entecavir drugs.

Remote control of diastereoselectivity in intramolecular reactions of chiral allylsilanes

During investigations of cyclization reactions between chiral allylsilanes and N-acyliminium ions, it was discovered that a suitably positioned benzyloxy group on the allylsilane component caused a reversal in the diastereoselectivity of these reactions r

Synthesis of the apoptosis inducing agent apoptolidin. Assembly of the C(16)-C(28) fragment.

[reaction--see text] A stereoselective synthesis of the C(16)-C(28) fragment of the apoptosis inducing agent apoptolidin is described. Key steps include two propionate aldol reactions and a stereoselective Mukaiyama aldol addition of enolsilane 19 to beta