93548-33-5

Basic information

• Product Name: 1-Cyclohexyl-1-pentanol
• CAS NO: 93548-33-5
• Molecular Formula: C₁₁H₂₂O
• Molecular Weight: 170.295
• Mol File: 93548-33-5.mol

Chemical Properties

• Boiling Point: 243.2°Cat760mmHg
• Flash Point: 107.9°C
• Density: 0.9g/cm³
• CAS DataBase Reference: 1-Cyclohexyl-1-pentanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclohexyl-1-pentanol(93548-33-5)
• EPA Substance Registry System: 1-Cyclohexyl-1-pentanol(93548-33-5)

Safety Data

• Hazardous Substances Data: 93548-33-5(Hazardous Substances Data)

Upstream product

• 110-62-3 pentanal 
• 931-50-0 cyclohexylmagnesium bromide 
• 109-72-8 n-butyllithium 
• 2043-61-0 cyclohexanecarbaldehyde 
• 108-05-4 vinyl acetate 
• 63126-49-8 (+/-)-1-cyclohexyl-1-pentanol 
• 5445-35-2 1-cyclohexyl-1-pentanone 
• 109-65-9 1-bromo-butane 
• 693-03-8 n-butyl magnesium bromide 
• 162843-19-8 CH₃Zn(CH₂)3CH₃ 
• 132841-63-5 (Z)-(1R,4R)-1-Cyclohexyl-4-(dimethyl-phenyl-silanyl)-pent-2-en-1-ol 
• 132841-63-5 (Z)-(1S,4R)-1-Cyclohexyl-4-(dimethyl-phenyl-silanyl)-pent-2-en-1-ol 
• 108-85-0 1-bromocyclohexane 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 5445-35-2 1-cyclohexyl-1-pentanone 
• 1197170-98-1 C₁₃H₂₄O₂ 
• 63126-49-8 (R)-(+)-1-cyclohexylpentanol 

Relevant articles and documents

Kinetic resolution of racemic allylic alcoholsviairidium-catalyzed asymmetric hydrogenation: scope, synthetic applications and insight into the origin of selectivity

Asymmetric hydrogenation is one of the most commonly used tools in organic synthesis, whereas, kinetic resolutionviaasymmetric hydrogenation is less developed. Herein, we describe the first iridium catalyzed kinetic resolution of a wide range of trisubstituted secondary and tertiary allylic alcohols. Large selectivity factors were observed in most cases (sup to 211), providing the unreacted starting materials in good yield with high levels of enantiopurity (ee up to >99%). The utility of this method is highlighted in the enantioselective formal synthesis of some bioactive natural products including pumiliotoxin A, inthomycin A and B. DFT studies and a selectivity model concerning the origin of selectivity are presented.

Catalytic asymmetric addition of aldehydes using organolithium reagents in the presence of commercial available chiral diol ligands

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Catalytic enantioselective addition of MeMgBr and other Grignard reagents to aldehydes

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Addition of RMgCl (R = n-Bu, Ph) to pinacol esters of 6-tosyloxy-l-alkenyl boronic acids at -78 °C gave the borates, which upon warming to room temperature underwent migration of R on boron to C(1) carbon and concomitant ring construction C-C bond formati

Empirical method for predicting enantioselectivity in catalytic reactions: demonstration with lipase and oxazaborolidine

We derived a novel equation capable of predicting the degree of enantioselectivity in a catalytic reaction without any knowledge of the reaction mechanism and/or the transition-state structure, and tested the validity of this equation by changing substrates systematically in the lipase or oxazaborolidine-catalyzed reactions. A good correlation was observed between the predicted and observed E values, and the stereochemistry of the products could be predicted correctly in most cases (28 out of 30).

Pentamethylcyclopentadienide in organic synthesis: Nucleophilic addition of lithium pentamethylcyclopentadienide to carbonyl compounds and carbon-carbon bond cleavage of the adducts yielding the parent carbonyl compounds

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Highly enantioselective 1,2-additions of various organolithium reagents to aldehydes

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