936344-74-0

Basic information

• Product Name: 3-ethynyl-5-fluoropyridin-2-amine
• Synonyms: 3-ethynyl-5-fluoropyridin-2-amine
• CAS NO: 936344-74-0
• Molecular Formula: C₇H₅FN₂
• Molecular Weight: 136.1264032
• Mol File: 936344-74-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-ethynyl-5-fluoropyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethynyl-5-fluoropyridin-2-amine(936344-74-0)
• EPA Substance Registry System: 3-ethynyl-5-fluoropyridin-2-amine(936344-74-0)

Safety Data

• Hazardous Substances Data: 936344-74-0(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
3-Ethynyl-5-fluoropyridin-2-amine is utilized as a building block for the synthesis of various pharmaceutical compounds. Its distinctive structure allows it to be a key component in the creation of new medications.
Used in Drug Discovery:
As a compound with potential biological activities, such as enzyme inhibition or receptor binding, 3-Ethynyl-5-fluoropyridin-2-amine serves as a valuable tool in the identification and development of novel drugs.
Used in Organic Synthesis:
3-Ethynyl-5-fluoropyridin-2-amine is an important intermediate in organic synthesis, where its specific structure and properties are harnessed to facilitate the creation of complex organic molecules.
Used in Pharmaceutical Research:
The unique structure and properties of 3-Ethynyl-5-fluoropyridin-2-amine make it a valuable tool for pharmaceutical research, aiding scientists in understanding and developing new therapeutic agents.

Upstream product

• 869557-43-7 3-bromo-5-fluoropyridin-2-amine 
• 21717-96-4 2-amino-5-fluoropyridine 
• 823218-51-5 5-fluoro-3-iodo-pyridin-2-amine 
• 866319-01-9 5-fluoro-3-(2-trimethylsilylethynyl)pyridine-2-amine 

Downstream Products

• 866319-00-8 5-fluoro-1H-pyrrolo[2,3‐b]pyridine 
• 1211524-51-4 2-amino-3-acetyl-5-fluoropyridine 
• 866318-99-2 5-fluoro-1-tosyl-1H-pyrrolo [2,3-b]pyridine 
• 1417421-99-8 3-bromo-5-fluoro-1-(p-toluenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 1259279-57-6 5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(p-toluenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 936341-61-6 3-(3-(4-benzyloxy-benzyl)-isoxazol-5-yl)-5-fluoro-pyridin-2-ylamine 

Relevant articles and documents

METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION

A method of preparing Compound (1) or a pharmaceutically acceptable salt thereof: comprises: (a) reacting Compound (X): a pharmaceutically acceptable salt thereof with Compound (Y): in the presence of a palladium catalyst and a carbonate or phosphate base

SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS

The invention pertains to heteroaromatic compounds of the formula I, as defined herein, that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.