869557-43-7

Basic information

• Product Name: 2-Amino-3-bromo-5-fluoropyridine
• Synonyms: 3-Bromo-5-fluoropyridin-2-amine;3-BroMo-5-fluoro-pyridin-2-ylaMine;2-Amino-3-bromo-5-fluoropyridine 97%;2-Pyridinamine, 3-bromo-5-fluoro-;2-AMINO-3-BROMO-5-FLUOROPYRIDINE;2-AMINO-5-FLUORO-3-BROMO PYRIDINE
• CAS NO: 869557-43-7
• Molecular Formula: C₅H₄BrFN₂
• Molecular Weight: 191
• Product Categories: Amines;blocks;FluoroCompounds;Pyridines;Boronic Acid;Building Blocks;C5;C5 to C6;Chemical Synthesis;Fluorinated Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;Fluorine series
• Mol File: 869557-43-7.mol
• Article Data: 11

Chemical Properties

• Melting Point: 61-63°C
• Boiling Point: 63-65℃
• Flash Point: 86.8 °C
• Appearance: /
• Density: 1.813 g/cm³
• Storage Temp.: Keep Cold
• PKA: 1.86±0.49(Predicted)
• CAS DataBase Reference: 2-Amino-3-bromo-5-fluoropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3-bromo-5-fluoropyridine(869557-43-7)
• EPA Substance Registry System: 2-Amino-3-bromo-5-fluoropyridine(869557-43-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• WGK Germany: 3
• Hazardous Substances Data: 869557-43-7(Hazardous Substances Data)

Usage

Uses

2-Amino-3-bromo-5-fluoropyridine is a reactant used in the synthesis of cyano heteroaryl bromides.

Upstream product

• 21717-96-4 2-amino-5-fluoropyridine 

Downstream Products

• 801303-22-0 2-amino-5-fluoronicotinonitrile 
• 866319-01-9 5-fluoro-3-(2-trimethylsilylethynyl)pyridine-2-amine 
• 866319-00-8 5-fluoro-1H-pyrrolo[2,3‐b]pyridine 
• 866318-99-2 5-fluoro-1-tosyl-1H-pyrrolo [2,3-b]pyridine 
• 1417421-99-8 3-bromo-5-fluoro-1-(p-toluenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 1259279-57-6 5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(p-toluenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 936344-74-0 3-ethynyl-5-fluoro-pyridin-2-ylamine 
• 1629869-44-8 pimodivir 
• 1187448-58-3 4-(2-cyclopropyl-5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)benzenesulfonamide 
• 1187448-62-9 4-(2-cyclopropyl-5-fluoro-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(2-hydroxyethyl)benzenesulfonamide 
• 1187449-21-3 4-bromo-2-cyclopropyl-5-fluoro-1H-pyrrolo[2,3-b]pyridine 
• 1187449-15-5 2-cyclopropyl-5-fluoro-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

FORMULATIONS OF AZAINDOLE COMPOUNDS

The present invention relates to pharmaceutical compositions, each comprising a multitude of granules that make up an intragranular phase of the composition, wherein the granules are produced by fluid bed granulation and comprise a HCI salt of Compound (1

METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION

A method of preparing a compound of Formula (I) or a pharmaceutically acceptable salt thereof comprises: (a) reacting Compound (1) or (b) a pharmaceutically acceptable salt thereof with Compound (2) in the presence of water, an organic solvent, a base, an

INHIBITORS OF INFLUENZA VIRUSES REPLICATION

Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula: are Form A of HCl salt of Compound (1)·1/2Η20, Form F of HCl salt of Compound (1)·3Η2