93648-88-5

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 23517-07-9 ((E)-1-(but-1-en-3-yn-1-yl)-4-methoxybenzene) 
• 100-63-0 phenylhydrazine 
• 24393-56-4 ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate 
• 53484-50-7 (E)-p-methoxy-cinnamyl alcohol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 75-56-9 methyloxirane 

Downstream Products

• 90276-22-5 5-(4-methoxy-phenyl)-3-methyl-1-phenyl-1H-pyrazole 

Relevant academic research and scientific papers

Synthesis of 1,3,5-trisubstituted pyrazolines via Zn(ii)-catalyzed double hydroamination of enynes with aryl hydrazines

An efficient Zn(ii)-catalyzed intermolecular double hydroamination of 1,3-enynes with aryl hydrazines, for the synthesis of pyrazolines, has been discussed.

Solid-phase synthesis of pyrazolines and isoxazolines with sodium benzenesulfinate as a traceless linker

(Matrix presented) The preparation of pyrazoline and isoxazoline derivatives with traceless solid-phase sulfone linker strategy is described. Key steps involved in the solid-phase synthetic procedure include (i) sulfinate S-alkylation, (ii) sulfone anion alkylation, (iii) γ-hydroxy sulfone → γ-ketosulfone oxidation, and (iv) traceless product release via elimination-cyclization. A library of 12 pyrazolines and isoxazolines was synthesized.