936716-48-2

Upstream product

• 936716-42-6 4-amino-2-{4-[2-(trifluoromethyl)phenoxy]piperidin-1-yl}-1,3-thiazole-5-carboxamide 
• 64-19-7 acetic acid 
• 75-36-5 acetyl chloride 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 444-30-4 2-(trifluoromethyl)phenol 
• 921605-76-7 tert-butyl 4-[2-(trifluoromethyl)phenoxy]-piperidine-1-carboxylate 
• 824390-04-7 4-(2-(trifluoromethyl)phenoxy)piperidine 

Downstream Products

• 1085784-46-8 ({2-[4-(2-trifluoromethylphenoxy)piperidin-1-yl]-5-methyl[1,3]thiazolo[4,5-d]pyrimidin-7-yl}oxy)acetic acid 
• 1085784-48-0 ethyl ({2-[4-(2-trifluoromethylphenoxy)piperidin-1-yl]-5-methyl[1,3]thiazolo[4,5-d]pyrimidin-7-yl}oxy)acetate 
• 1085784-47-9 2-[4-(2-trifluoromethylphenoxy)piperidin-1-yl]-7-chloro-5-methyl[1,3]thiazolo[4,5-d]pyrimidine 

Relevant academic research and scientific papers

BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Bicyclic heteroaromatic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis

AZACYCLOHEXANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE

Azacyclohexane derivatives of structural formula I are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis.