93758-59-9Relevant academic research and scientific papers
Design, synthesis and anticancer activity evaluation of diazepinomicin derivatives
Yu, Yongguo,Wu, Jianbo,Lei, Fan,Chen, Lei,Wan, Weili,Hai, Li,Guan, Mei,Wu, Yong
, p. 369 - 373 (2013/07/26)
A series of diazepinomicin derivatives were synthesized and evaluated in vitro for their growth inhibitory activity against the human carcinoma cell lines. The results indicated the anticancer selectivity of this kind of compounds. Based on the results, preliminary structure-activity relationships were discussed.
Antiproliferative and differentiating activities of a novel series of histone deacetylase inhibitors
Binaschi, Monica,Boldetti, Andrea,Gianni, Maurizio,Maggi, Carlo Alberto,Gensini, Martina,Bigioni, Mario,Parlani, Massimo,Giolitti, Alessandro,Fratelli, Maddalena,Valli, Claudia,Terao, Mineko,Garattini, Enrico
scheme or table, p. 411 - 415 (2011/01/13)
Histone deacetylases are promising molecular targets for the development of antitumor agents. A novel series of histone deacetylase inhibitors of the hydroxamic acid type were synthesized for structure-activity studies. Thirteen tricyclic dibenzo-diazepin
