94077-46-0

Basic information

• Product Name: (1S,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol
• Synonyms: (1S,2R)-2-Amino-1-indanol;(1S,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol
• CAS NO: 94077-46-0
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149
• Mol File: 94077-46-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 297℃
• Flash Point: 133℃
• Appearance: /
• Density: 1.212
• CAS DataBase Reference: (1S,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol(94077-46-0)
• EPA Substance Registry System: (1S,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol(94077-46-0)

Safety Data

• Hazardous Substances Data: 94077-46-0(Hazardous Substances Data)

Usage

General Description

The chemical (1S,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol is a compound with the molecular formula C9H11NO. It is a chiral molecule, containing both an amine group and a hydroxyl group. Its IUPAC name is (1S,2R)-2-Amino-1,2-dihydro-1H-inden-1-ol. (1S,2R)-2-Amino-2,3-dihydro-1H-inden-1-ol has potential applications in pharmaceutical and medicinal chemistry, particularly in the development of new drugs and therapeutic agents. Its unique structure and functional groups make it a valuable building block for the synthesis of organic molecules with biological activity. Further research into its properties and potential uses could lead to new discoveries in the field of drug development and medicinal chemistry.

Upstream product

• 13575-72-9 2-amino-1-indanol 
• 171482-71-6 (1R,2R)-2-azido-2,3-dihydro-1H-inden-1-ol 
• 2338-18-3 2-aminoindane hydrochloride 
• 166942-30-9 (1S,2R)-2-azido-2,3-dihydro-1H-inden1-ol 
• 171285-94-2 (1R,2R)-2-azido-2,3-dihydro-1H-inden-1-yl-4-nitrobenzoate 
• 15028-10-1 indan-1,2-dione-2-oxime 
• 29365-64-8 (1R,2R)-(-)-2-phthalimidoindan-1-ol 
• 74036-09-2 2-(1-oxo-indan-2-yl)-isoindole-1,3-dione 
• 83-33-0 inden-1-one 
• 1775-27-5 2-bromoindanone 

Downstream Products

• 94077-09-5 (-)-(2RS,4R,5S)-2-phenyl-3,3a,4,8b-tetrahydro-2H-indeno<2,1-d>oxazole 
• 94077-02-8 (1R,2R)-2-{[1-Phenyl-meth-(E)-ylidene]-amino}-indan-1-ol 
• 144285-04-1 (1S,2R)-2-(2-hydroxybenzylideneamino)-1-indanol 
• 144285-04-1 (1R,2R)-2-(2-hydroxybenzylideneamino)-1-indanol 
• 94077-03-9 (1R,2R)-2-{[1-(3-Methoxy-phenyl)-meth-(E)-ylidene]-amino}-indan-1-ol 
• 94077-04-0 (1R,2R)-2-{[1-(2,3-Dimethoxy-phenyl)-meth-(E)-ylidene]-amino}-indan-1-ol 
• 23672-01-7 (-)-(1S,2R)-2-benzylaminoindan-1-ol 
• 23672-01-7 (-)-(1R,2R)-2-benzylaminoindan-1-ol 
• 94077-17-5 (1R,2R)-2-(3-Methoxy-benzylamino)-indan-1-ol 
• 94077-19-7 (1R,2R)-2-(2,3-Dimethoxy-benzylamino)-indan-1-ol 

Relevant articles and documents

Practical Synthetic Procedures for the Iron-Catalyzed Intermolecular Olefin Aminohydroxylation Using Functionalized Hydroxylamines

A set of practical synthetic procedures for the iron-catalyzed intermolecular olefin aminohydroxylation reactions in gram scale is reported. In these transformations, a bench-stable functionalized hydroxylamine is applied as the amination reagent. This method is compatible with a broad range of synthetically valuable olefins including those that are incompatible with the existing aminohydroxylation methods. It also provides valuable amino alcohol building blocks with regio- and stereochemical arrays that are complementary to known methods.

Stereoselective synthesis of 1,2-amino alcohols by asymmetric borane reduction of α-oxoketoxime ethers

Asymmetric reduction of α-oxoketoxime ethers with the reagents prepared in situ from trimethyl borate and chiral amino alcohols derived from either L-proline or α-pinene was investigated. Both cyclic and acyclic α- oxoketoxime ethers were reduced to afford the corresponding chiral 1,2amino alcohols with high enantioselectivities.

Synthesis of Enantiomerically Pure cis and trans-2-Amino-1-indanol

Enantiomerically pure cis and trans-2-amino-1-indanols 1 and 2 were synthesized via a highly enetioslective lipase catalyzed transestrification of racemic cis-2-azido-1-indanol 3.