94166-58-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Aminopyridine is used as a key intermediate for the synthesis of pharmaceuticals, particularly anti-inflammatory and analgesic drugs. Its unique structure allows for the development of various therapeutic agents that can effectively manage pain and inflammation.
Used in Agrochemical Industry:
2-Aminopyridine is used as a building block in the production of herbicides. Its incorporation into these chemical compounds helps in the development of effective weed control agents that can protect crops and enhance agricultural productivity.
Used in Dye and Pigment Industry:
2-Aminopyridine is used in the synthesis of dyestuffs, contributing to the development of a wide range of colors and pigments used in various applications, including textiles, plastics, and printing inks.
Used in Organic Synthesis:
2-Aminopyridine is used as a catalyst and ligand in organic synthesis, facilitating various chemical reactions and improving the efficiency of synthetic processes. Its unique properties make it a valuable component in the development of new chemical compounds and materials.
Used in Catalyst and Ligand Production:
2-Aminopyridine is used in the production of catalysts and ligands, which are essential in various chemical processes. Its presence in these compounds enhances their performance and contributes to the advancement of chemical synthesis techniques.

InChI:InChI=1/C7H9N3O3/c1-8-7-5(10(11)12)3-4-6(9-7)13-2/h3-4H,1-2H3,(H,8,9)

Upstream product

• 124-41-4 sodium methylate 
• 33742-70-0 6-chloro-N-methyl-3-nitropyridin-2-amine 
• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 38533-61-8 2-chloro-6-methoxy-3-nitropyridine 
• 74-89-5 methylamine 

Downstream Products

• 172648-25-8 5-[4-(5-methoxy-3-methyl-3H-imidazo[4,5-b]pyridin-2-ylmethoxy)benzyl]-3-triphenylmethylthiazolidine-2,4-dione 
• 90817-34-8 3-amino-6-methoxy-2-(methylamino)-pyridine 

Relevant academic research and scientific papers

Design, Synthesis, and Fungicidal Activity of Novel Imidazo[4,5-b]pyridine Derivatives

A series of novel imidazo[4,5-b]pyridine derivatives were designed and synthesized. The structures of all the newly synthesized compounds were identified by spectroscopic data NMR, MS, and elemental analysis. Bioassay showed that the compounds exhibited potent fungicidal activities against Erysiphe graminis, Puccinia polysora, and so forth. Particularly, 2-chloro-5-((5-methoxy-2-(2-(trifluoromethyl)phenyl)-3H-imidazo[4,5-b]pyridin-3-yl)methyl)thiazole (9b) displayed fungicidal potency against P.?polysora. Its EC50 value: 4.00?mg/L is comparable with that of tebuconazole. The structure–activity relationship for the target compounds is discussed.

Molecular design, synthesis, and hypoglycemic activity of a series of thiazolidine-2,4-diones

A series of imidazopyridine thiazolidine-2,4-diones were designed and synthesized from their corresponding pyridines. These compounds represent conformationally restricted analogues of the novel hypoglycemic compound rosiglitazone (5). The series was evaluated for its effect on insulin-induced 3T3-L1 adipocyte differentiation in vitro and its hypoglycemic activity in the genetically diabetic KK mouse in vivo. The structure-activity relationships are discussed. On the basis of the in vivo potency, 5-[4-(5-methoxy-3-methyl-3H-imidazo[4,5-b]pyridin-2-ylmethoxy)ben zyl]thiazolidine-2,4-dione (19a) was selected as the candidate for further studies in a clinical setting.

Heterocyclic compounds having anti-diabetic activity and their use

Compounds of formula (I): STR1 [wherein: X represents an unsubstituted or substituted indolyl, indolinyl, azaindolyl, azaindolinyl, imidazopyridyl or imidazopyrimidinyl group; Y represents an oxygen or sulfur atom; Z represents a 2,4-dioxothiazolidin-5-ylidenylmethyl, 2,4-dioxothiazolidin-5-ylmethyl, 2,4-dioxooxazolidin-5-ylmethyl, 3,5-dioxooxadiazolidin-2-ylmethyl or N-hydroxyureidomethyl group; R represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, a hydroxy group, a nitro group, an aralkyl group or a unsubstituted or substituted amino group; and m is an integer of from 1 to 5] have hypoglycemic and anti-diabetic activities.