941693-40-9

Upstream product

• 941693-37-4 2-bromo-4,6-dimethyl-3,5-dicarbonitrile 
• 4039-83-2 3-(4-methoxybenzyloxy)propyne 
• 123-54-6 acetylacetone 
• 105-13-5 4-Methoxybenzyl alcohol 
• 6497-21-8 1-(5-methyl-1,2-oxazol-4-yl)ethanone 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 18856-72-9 3-dimethylaminomethylenepentane-2,4-dione 
• 23819-87-6 5-bromo-2-hydroxy-4,6-dimethyl-nicotinonitrile 
• 769-28-8 2-hydroxy-4,6-dimethyl-3-carbonitrile 
• 109703-07-3 C₉H₇N₃O 
• 941693-30-7 2-methyl-4-oxo-3-(phenylamino)pent-2-enenitrile 

Downstream Products

• 941693-43-2 2-(3-(4-methoxybenzyloxy)propyl)-4,6-dimethylpyridine-3,5-dicarbonitrile 
• 941693-23-8 2-(3-(4-methoxybenzyloxy)propyl)-4,6-dimethylpyridine-3,5-dicarbaldehyde 

Relevant academic research and scientific papers

The natural product CCR5 antagonist anibamine and its analogs as anti-prostate cancer agents

Prostate cancer is a leading cause of death among males in the United States. As the chemokine receptor CCR5 is over-expressed in more aggressive forms of prostate cancer, and is also a critical receptor in inflammation, chemokine receptor CCR5 antagonist

Total synthesis of anibamine, a novel natural product as a chemokine receptor CCR5 antagonist

The total synthesis of anibamine, the first and only natural product known as a chemokine receptor OCR5 antagonist, is reported herein. Anibamine was synthesized from acetylacetone and cyanoacetamide in 10 steps.