94348-27-3

Upstream product

• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 100-52-7 benzaldehyde 
• 201230-82-2 carbon monoxide 
• 5720-07-0 4-methoxyphenylboronic acid 
• 501-65-5 diphenyl acetylene 
• 123-11-5 4-methoxy-benzaldehyde 
• 50-00-0 formaldehyd 
• 7474-65-9 (E)-2-phenylchalcone 

Relevant academic research and scientific papers

Stereo-controlledanti-hydromagnesiation of aryl alkynes by magnesium hydrides

A concise protocol foranti-hydromagnesiation of aryl alkynes was established using 1?:?1 molar combination of sodium hydride (NaH) and magnesium iodide (MgI2) without the aid of any transition metal catalysts. The resulting alkenylmagnesium intermediates could be trapped with a series of electrophiles, thus providing facile accesses to stereochemically well-defined functionalized alkenes. Mechanistic studies by experimental and theoretical approaches imply that polar hydride addition from magnesium hydride (MgH2) is responsible for the process.

Rhodium(I)-catalyzed carbonylative arylation of alkynes with arylboronic acids using formaldehyde as a carbonyl source

The rhodium(I)-catalyzed reaction of alkynes with arylboronic acids in the presence of formaldehyde resulted in a carbon monoxide gas-free carbonylative arylation to yield α,β-enones. The simultaneous loading of phosphine-ligated and phosphine-free rhodium(I) complexes is required for efficient catalysis, which catalyze the abstraction of a carbonyl moiety from formaldehyde (decarbonylation) and its subsequent introduction into the substrate (carbonylation), respectively. Georg Thieme Verlag Stuttgart New York.

Ruthenium-catalyzed intermolecular hydroacylation of internal alkynes: The use of ceria-supported catalyst facilitates the catalyst recycling

Versatile and practical: Intermolecular hydroacylation of internal alkynes takes place in the presence of Ru catalysts together with HCO2Na and Xantphos to give the corresponding conjugated enones. Aromatic aldehydes with or without coordinatin

Rhodium catalyzed reaction of internal alkynes with organoborons under CO atmosphere: a product tunable reaction

Alkynes react with organoborons under a CO atmosphere in the presence of a rhodium(I) catalyst to afford mainly 5-aryl-2(5H)-furanones, α,β-unsaturated ketones, and indanones. The product selectivity can be tuned by modifying the reaction conditions.

Synthesis of α,β-unsaturated ketones by rhodium-catalyzed carbonylative arylation of internal alkynes with arylboronic acids

The Rh-catalyzed reaction of arylboronic acids with internal alkynes under a CO atmosphere in the presence of an acid additive afforded α,β-unsaturated ketones as the major products. Hydroacylation of internal alkynes, except in the case of diaryl acetylenes, proceeded in syn fashion, yielding the E-configured isomer. A mixture of E- and Z-isomers was obtained with diphenyl acetylene. Reactions were also highly regioselective for various nonsymmetric alkynes.

Antifertility Agents: Part 52-Synthesis and Antiimplantation Study of 4,5-trans/cis-1-Acetyl-3,4,5-triarylpyrazolines

The reaction of 2-phenyl-p-methoxyacetophenone (1) with benzaldehyde or p-hydroxybenzaldehyde gives E- and Z-isomers of 1,2,3-triarylpropen-1-ones (2e,z and 3e,z).Condensation of the E-isomer of 2 (2e) and 3e,z with hydrazine hydrate affords a mixture of

Structure-Activity Relationship of Estrogens: Receptor Affinity and Estrogen Antagonist Activity of Certain (E)- and (Z)-1,2,3-Triaryl-2-propen-1-ones

(E)- nad (Z)-1,2,3-triphenyl-2-propen-1-ones and some of their phenolic and alkoxy analogues, substituted at the para position in one or more aromatic rings, were synthesized and assigned geometry on the basis on their spectroscopic data.The structure-act