943906-71-6

Basic information

• Product Name: 2,4-dibromophenethyl alcohol
• Synonyms: 2,4-dibromophenethyl alcohol
• CAS NO: 943906-71-6
• Molecular Weight: 279.959
• Mol File: 943906-71-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-dibromophenethyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dibromophenethyl alcohol(943906-71-6)
• EPA Substance Registry System: 2,4-dibromophenethyl alcohol(943906-71-6)

Safety Data

• Hazardous Substances Data: 943906-71-6(Hazardous Substances Data)

Usage

General Description

2,4-dibromophenethyl alcohol is a chemical compound with the molecular formula C8H9Br2O. It is a white crystalline solid with a faint, sweet odor. 2,4-dibromophenethyl alcohol is used in the synthesis of various pharmaceutical and agrochemical products. It also has potential applications in organic synthesis and as a building block for the creation of more complex chemical compounds. Additionally, 2,4-dibromophenethyl alcohol is used in the manufacturing of certain dyes and perfumes. However, it is important to handle this substance with care, as it is considered harmful if ingested or inhaled and can cause irritation to the skin and eyes.

Upstream product

• 78222-69-2 2,4-dibromobenzonitrile 
• 666747-06-4 (2,4-dibromophenyl)methanol 
• 615-57-6 2,4-dibromo-aniline 
• 5629-98-1 2,4-dibromobenzaldehyde 
• 98434-44-7 (2,4-dibromophenyl)acetic acid 
• 66246-16-0 2-(2,4-dibromophenyl)acetonitrile 

Relevant articles and documents

Synthesis and biological studies of novel 2-aminoalkylethers as potential antiarrhythmic agents for the conversion of atrial fibrillation

A series of 2-aminoalkylethers prepared as potential antiarrhythmic agents is described. The present compounds are mixed sodium and potassium ion channel blockers and exhibit antiarrhythmic activity in a rat model of ischemia-induced arrhythmias. Structure-activity studies led to the identification of three compounds 5, 18, and 26, which were selected based on their particular in vivo electrophysiological properties, for studies in two canine atrial fibrillation (AF) models. The three compounds converted AF in both models, but only compound 26 was shown to be orally bioavailable. Resolution of the racemate 26 into its corresponding enantiomers 40 and 41 and subsequent biological testing of these enantiomers led to the selection of (1S,2S)-1-(1-naphthalenethoxy)-2-(3- ketopyrrolidinyl)cyclohexane monohydrochloride (41) as a potential atrial selective antiarrhythmic candidate for further development.