98434-44-7

Basic information

• Product Name: 2,4-Dibromobenzeneacetic acid
• Synonyms: 2,4-Dibromobenzeneacetic acid;2-(2,4-Dibromophenyl)acetic acid
• CAS NO: 98434-44-7
• Molecular Formula: C₈H₆Br₂O₂
• Molecular Weight: 294
• Mol File: 98434-44-7.mol

Chemical Properties

• Melting Point: 141-142℃
• Appearance: /
• Density: 1.969
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2,4-Dibromobenzeneacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dibromobenzeneacetic acid(98434-44-7)
• EPA Substance Registry System: 2,4-Dibromobenzeneacetic acid(98434-44-7)

Safety Data

• Hazardous Substances Data: 98434-44-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Dibromobenzeneacetic acid is used as a reagent in the synthesis of various pharmaceuticals for its high reactivity, contributing to the development of new drugs and medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-Dibromobenzeneacetic acid is employed as a building block for the synthesis of agrochemicals, playing a role in the production of pesticides and other agricultural chemicals that protect crops and enhance yields.
Used in Dye Industry:
2,4-Dibromobenzeneacetic acid is used as a precursor in the dye industry, where it is involved in the production of various dyes used in textiles, printing, and other applications.
Used in Organic Synthesis:
As a reagent in organic synthesis, 2,4-Dibromobenzeneacetic acid is utilized for its high reactivity, facilitating the creation of a broad spectrum of organic compounds for research and commercial purposes.

Upstream product

• 78222-69-2 2,4-dibromobenzonitrile 
• 666747-06-4 (2,4-dibromophenyl)methanol 
• 615-57-6 2,4-dibromo-aniline 
• 5629-98-1 2,4-dibromobenzaldehyde 
• 66246-16-0 2-(2,4-dibromophenyl)acetonitrile 

Downstream Products

• 943906-71-6 2,4-dibromophenethyl alcohol 

Relevant articles and documents

Synthesis and biological studies of novel 2-aminoalkylethers as potential antiarrhythmic agents for the conversion of atrial fibrillation

A series of 2-aminoalkylethers prepared as potential antiarrhythmic agents is described. The present compounds are mixed sodium and potassium ion channel blockers and exhibit antiarrhythmic activity in a rat model of ischemia-induced arrhythmias. Structure-activity studies led to the identification of three compounds 5, 18, and 26, which were selected based on their particular in vivo electrophysiological properties, for studies in two canine atrial fibrillation (AF) models. The three compounds converted AF in both models, but only compound 26 was shown to be orally bioavailable. Resolution of the racemate 26 into its corresponding enantiomers 40 and 41 and subsequent biological testing of these enantiomers led to the selection of (1S,2S)-1-(1-naphthalenethoxy)-2-(3- ketopyrrolidinyl)cyclohexane monohydrochloride (41) as a potential atrial selective antiarrhythmic candidate for further development.

The first syntheses of 3-bromofascaplysin, 10-bromofascaplysin and 3,10-dibromofascaplysin-marine alkaloids from Fascaplysinopsis reticulata and Didemnum sp. by application of a simple and effective approach to the pyrido[1,2-a:3,4-b′]diindole system

A simple and practical approach for the synthesis of the marine sponge pigment fascaplysin was used for the total syntheses of its natural derivatives, the marine alkaloids 3-bromofascaplysin, 10-bromofascaplysin, and 3,10-dibromofascaplysin. The conditions of each step were revised, and as a result these compounds were produced by identical procedures with total yields of 40-43%.