94480-29-2Relevant articles and documents
A concise and efficient synthesis of spiroketals - Application to the synthesis of SPIKET-P and a spiroketal from bactrocera species
Tomas, Loic,Bourdon, Benjamin,Caille, Jean Claude,Gueyrard, David,Goekjian, Peter G.
, p. 915 - 920 (2013/03/28)
We report the synthesis of spiroketals by sequence of enol ether synthesis and cyclization. The enol ethers were prepared from lactones by a Julia olefination reaction, and the starting chiral lactone was prepared from an industrial intermediate. This route is a concise and efficient way to synthesize naturally occurring and biologically interesting spiroketals. We used this sequence for the preparation of SPIKET-P and a spiroketal from Bactrocera species. Copyright
Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions
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Page/Page column 23-24; 33-34, (2010/11/27)
Methods of performing cycloadditions are described that include (a) combining a first reactant and a second reactant in a hydrogen bonding solvent to form a reaction mixture; and (b) reacting the first reactant and the second reactant to form a cycloadduc
Optically active maleimide derivatives and polymaleimides for use as chiral adsorbent in chromatography
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Page 12; 13, (2010/02/09)
An optically active maleimide dericative represented by the following formula (1): as well as the polymer synthesized therefrom. The polymers are useful as chival adsorbents in chomatography.
A new dirhodium(II) carboxamidate complex as a chiral Lewis acid catalyst for enantioselective hetero-Diels-Alder reactions
Anada, Masahiro,Washio, Takuya,Shimada, Naoyuki,Kitagaki, Shinji,Nakajima, Makoto,Shiro, Motoo,Hashimoto, Shunichi
, p. 2665 - 2668 (2007/10/03)
Excellent enantioselectivities (up to 99% ee) and turnover numbers (up to 48000) were attained in the hetero-Diels-Alder reaction of a diverse range of aldehydes and activated dienes catalyzed by [Rh2(S-bptpi) 4] (see scheme).
Preparation and reactions of 2-allyl-5-deoxymannose derivatives
Saleh, Twana,Rousseau, Gérard
, p. 2891 - 2897 (2007/10/03)
Reaction of Danishefsky diene with benzyloxyethanal led to a pyrone which was transformed in 4-6 steps to different 5-deoxymannose derivatives, useful intermediates for the synthesis of natural product such as hemibrevetoxin.
A highly enantioselective hetero-Diels-Alder reaction of aldehydes with Danishefsky's diene catalyzed by chiral titanium(IV) 5,5′,6,6′,7,7′,8,8′-octahydro-1,1′ -bi-2-naphthol complexes
Wang, Bin,Feng, Xiaoming,Huang, Yaozong,Liu, Hui,Cui, Xin,Jiang, Yaozhong
, p. 2175 - 2182 (2007/10/03)
The catalytic effect of chiral Lewis acids on the hetero-Diels-Alder reaction between aldehydes and Danishefsky's diene (1) has been investigated. A variety of combinations of different ligands and Lewis acids have been examined as catalysts for the heter
Synthetic studies of antitumor macrolide laulimalide: Enantioselective synthesis of the C3-C14 segment by a catalytic hetero Diels-Alder strategy
Ghosh, Arun K.,Mathivanan, Packiarajan,Cappiello, John
, p. 2427 - 2430 (2007/10/03)
The C3-C14 segment of the novel antitumor agent laulimalide has been constructed enantioselectively by utilizing a catalytic asymmetric hetero Diels-Alder reaction of benzyloxyacetaldehyde and Danishefsky's diene followed by Ferrier rearrangement and asymmetric conjugate reaction as the key steps.
A Nitrile Oxide Based Entry to 2,3-Dihydropyran-4-ones. Synthesis of a Protected Version of "Compactin Lactone" in Racemic and Optically Active Forms
Kozikowski, Alan P.,Li, Chun-Sing
, p. 778 - 785 (2007/10/02)
The use of nitrile oxides bearing a masked β-oxo group as β-hydroxy-3-oxopropionylating agents for the vicinal functionalization of olefins is described.The β-hydroxy ketones revealed on hydrogenation of the initially formed 1,3-dipolar cycloaddition prod
