946-12-3 Usage
Uses
Used in Pharmaceutical Industry:
6-Methoxybenzothiazole-2-carboxamide is used as a building block for the synthesis of medicinal compounds due to its potential therapeutic properties, which have shown promise in biological assays. It aids in the development of new drugs with anticancer and antimicrobial capabilities.
Used in Analytical Chemistry:
6-Methoxybenzothiazole-2-carboxamide is used as a fluorescent probe for the detection of metal ions, making it a valuable tool in the field of analytical chemistry for environmental monitoring and other applications.
Used in Environmental Research:
Identified as a potential environmental pollutant, 6-Methoxybenzothiazole-2-carboxamide has implications for human health and the environment. It is a subject of further research to understand its uses, properties, and potential risks associated with its presence in the environment.
Further research is necessary to fully explore the applications, properties, and potential risks of 6-Methoxybenzothiazole-2-carboxamide, ensuring its safe and effective use in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 946-12-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,4 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 946-12:
(5*9)+(4*4)+(3*6)+(2*1)+(1*2)=83
83 % 10 = 3
So 946-12-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O2S/c1-13-5-2-3-6-7(4-5)14-9(11-6)8(10)12/h2-4H,1H3,(H2,10,12)
946-12-3Relevant academic research and scientific papers
A new application of the mild thiolation concept for an efficient three-step synthesis of 2-cyanobenzothiazoles: A new approach to Firefly-luciferin precursors
Wuerfel, Hendryk,Weiss, Dieter,Beckert, Rainer,Guether, Angelika
experimental part, p. 9 - 16 (2012/07/01)
An easy, low cost and upscalable three-step synthesis of Firefly luciferin precursors is presented. The 6-alkoxy-2-cyano-benzothiazoles (1) were synthesized starting from easily available O-alkylated 4-aminophenoles (2) via a mild thiolation, Jacobsen cyclization and dehydratization sequence.
New approach to the synthesis of 2-carbamoylbenzothiazoles
Yarovenko, V. N.,Stoyanovich, F. M.,Zolotarskaya, O. Yu.,Chernoburova, E. I.,Zararzin, I. V.,Krayushkin, M. M.
, p. 144 - 147 (2007/10/03)
The reactions of substituted anilines with chloroacetamide and sulfur in the presence of triethylamine afforded monothiooxamides. When treated with K3Fe(CN)6, the latter underwent cyclization to form 2-carbamoyIbenzothiazoles. The reactions were accompanied by the formation of the corresponding thiooxanilic acids, which also underwent cyclization to form benzothiazole-2-carboxylic acids.
