13599-84-3

Basic information

• Product Name: 6-Benzothiazolol(7CI,8CI,9CI)
• Synonyms: 6-Benzothiazolol(7CI,8CI,9CI);6-hydroxybenzothiazole;6-Benzothiazolol;6-Hydroxybenzothiazol
• CAS NO: 13599-84-3
• Molecular Formula: C₇H₅NOS
• Molecular Weight: 151.19
• Product Categories: BENZOTHIAZOLE
• Mol File: 13599-84-3.mol
• Article Data: 14

Chemical Properties

• Melting Point: 185.0 to 189.0 °C
• Boiling Point: 311.6 °C at 760 mmHg
• Flash Point: 142.3 °C
• Appearance: /
• Density: 1.444 g/cm³
• Vapor Pressure: 0.000304mmHg at 25°C
• Refractive Index: 1.745
• Storage Temp.: -20°C
• Solubility: soluble in Methanol
• PKA: 8.52±0.40(Predicted)
• CAS DataBase Reference: 6-Benzothiazolol(7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Benzothiazolol(7CI,8CI,9CI)(13599-84-3)
• EPA Substance Registry System: 6-Benzothiazolol(7CI,8CI,9CI)(13599-84-3)

Safety Data

• Hazardous Substances Data: 13599-84-3(Hazardous Substances Data)

Usage

General Description

6-Benzothiazolol(7CI,8CI,9CI) is a benzothiazole derivative, a specific type of heterocyclic compound. It is known to exhibit useful chemical and physical properties that make it suitable for various applications. As a heterocyclic compound, it contains atoms of at least two different elements in its ring structure. Benzothiazoles are known for their therapeutic properties and are used as synthetic precursors for a variety of chemical substances. However, specifics about this particular benzothiazole derivative such as its toxicity, safety measures, usage, and other properties are not readily available or are yet to be researched.

InChI:InChI=1/C7H5NOS/c9-5-1-2-6-7(3-5)10-4-8-6/h1-4,9H

Upstream product

• 1747-60-0 6-methoxybenzothiazol-2-ylamine 
• 106-51-4 p-benzoquinone 
• 533-30-2 1,3-benzothiazol-6-amine 
• 884-22-0 6-methoxy-benzothiazole-2-carboxylic acid methyl ester 
• 946-13-4 6-methoxybenzo[d]thiazol-2-carboxylic acid 
• 18522-99-1 ethyl 4'-methoxyoxanilate 
• 6274-29-9 2-amino-5-methoxy-thiophenol 
• 389135-55-1 Ethyl 2-ethoxy-7-hydroxy-2H-benzo[1,4]thiazine-3-carboxylate 
• 389135-58-4 Methyl 2-methoxy-7-hydroxy-2H-benzo[1,4]thiazine-3-carboxylate 
• 129058-56-6 methyl 6-hydroxybenzo[d]thiazole-2-carboxylate 
• 59587-30-3 6-hydroxy-benzothiazole-2-carboxylic acid ethyl 
• 129058-50-0 6-hydroxybenzo[d]thiazole-2-carboxylic acid 
• 946-12-3 6-methoxybenzothiazole-2-carboxamide 
• 2942-13-4 6-methoxy-1,3-benzothiazole 

Downstream Products

• 50605-82-8 3-(benzothiazol-6-yloxy)-1,2-epoxypropane 
• 186182-22-9 6-[[(1,1-dimethylethyl)diphenylsilyl]oxy]benzothiazole 
• 2835-05-4 2-amino-5-hydroxy-benzenesulfonic acid 
• 1246271-20-4 6-benzyloxy-1,3-benzothiazole 
• 26278-79-5 2-amino-6-hydroxybenzothiazole 
• 1344979-77-6 6-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)benzo-[d]thiazole-2-carbonitrile 
• 1361253-12-4 [6-(benzyloxy)-1,3-benzothiazol-2-yl][3-(tert-butyldimethylsilanyloxy)-4-methylphenyl]methanol 
• 1361253-13-5 [6-(benzyloxy)-1,3-benzothiazol-2-yl][3-(tert-butyldimethylsilanyloxy)-4-methylphenyl]methanone 
• 1361252-76-7 [6-(benzyloxy)-1,3-benzothiazol-2-yl](3-hydroxy-4-methylphenyl)methanone 

Relevant articles and documents

-

-

Method for synthesizing benzothiazole by microwave radiation of benzothioamide compound in aqueous phase

The invention discloses a method for synthesizing benzothiazole by microwave radiation of a benzothioamide compound in an aqueous phase. The method includes the steps: adding the benzothioamide compound into the aqueous phase under microwave conditions; performing cyclization under alkaline conditions to generate the benzothiazole. The method for preparing the benzothiazole is environmentally friendly, simple and convenient in operation, safe, cheap and efficient. Compared with the prior art, the method is applicable to a lot of functional groups, high in yield, few in by-products, simple in operation, safe, low in cost and environmentally friendly.

Processes and intermediates for the preparation of N4-phenyl-quinazoline-4-amine derivatives

This invention provides compounds of Formula (I), wherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.