946-13-4

Usage

Chemical Properties

Yellow solid

InChI:InChI=1/C9H7NO3S/c1-13-5-2-3-6-7(4-5)14-8(10-6)9(11)12/h2-4H,1H3,(H,11,12)

Upstream product

• 18522-99-1 ethyl 4'-methoxyoxanilate 
• 946-61-2 1-Thio-oxalsaeure-1-<4-methoxy-anilid> 
• 946-12-3 6-methoxybenzothiazole-2-carboxamide 
• 71369-81-8 2-(4-methoxyphenylamino)-2-thioxoacetamide 
• 2942-13-4 6-methoxy-1,3-benzothiazole 
• 124-38-9 carbon dioxide 
• 943-03-3 2-cyano-6-methoxybenzothiazole 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 884-22-0 6-methoxy-benzothiazole-2-carboxylic acid methyl ester 
• 71368-35-9 6-methoxybenzo[d]thiazole-2-carbothioamide 
• 939-69-5 2-cyano-6-hydroxybenzothiazole 
• 55318-95-1 2-Carbamoyl-6-hydroxybenzothiazin 
• 34500-31-7 (R)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid 
• 2591-17-5 D-luciferin 
• 20240-21-5 D-luciferin 
• 20115-09-7 2-(6’-hydroxy-2'-benzothiazolyl)-thiazole-4-carboxylic acid 
• 13599-84-3 6-hydroxybenzothiazole 
• 478165-98-9 6-methoxybenzothiazole-2-carboxylic acid hydrazide 
• 129058-56-6 methyl 6-hydroxybenzo[d]thiazole-2-carboxylate 
• 129058-50-0 6-hydroxybenzo[d]thiazole-2-carboxylic acid 

Relevant academic research and scientific papers

Neurodegenerative Therapies

The present invention provides a compound of formula (I) wherein: Y represents a C or N atom which may be substituted or form a cyclic group with R′″ but may not be a quaternary C atom; R′ is —OR1, —CONH2, —CF3, F, —OH, —NO2, —CN or —OCOR1 in which R1, is C1-3 alkyl and each may be in the beta or gamma position; R″ is C1-3 alkyl or H; and R′″ is H or a group consisting of 1-12 non-hydrogen atoms and may be linear, branched and/or incorporate one or more cyclic groups, cyclic groups may be aromatic and/or heterocyclic and 2 or more cyclic groups may be linked or fused and each may be substituted; or a salt, hydrate or solvate of a compound of formula (I) for use in the treatment or prevention of a neurodegenerative disorder by inhibiting formation of neurofibrillary (tau) tangles and/or by inhibiting Dyrk 1A. The invention further relates to non-therapeutic uses of these compounds.

Direct C-H carboxylation with carbon dioxide using 1,2,3-triazol-5-ylidene copper(I) complexes

1,2,3-Triazol-5-ylidene copper(I) complexes (tzNHC-Cu) efficiently catalyzed the direct C-H carboxylation of benzoxazole and benzothiazole derivatives with CO2 to give the corresponding esters in excellent yields after treatment with alkyl iodi

New approach to the synthesis of 2-carbamoylbenzothiazoles

The reactions of substituted anilines with chloroacetamide and sulfur in the presence of triethylamine afforded monothiooxamides. When treated with K3Fe(CN)6, the latter underwent cyclization to form 2-carbamoyIbenzothiazoles. The reactions were accompanied by the formation of the corresponding thiooxanilic acids, which also underwent cyclization to form benzothiazole-2-carboxylic acids.

Photochromic dihetarylethenes. 12.* Synthesis of 5-alkyl-2- (1,3,4-oxadiazol-2-yl)thiophenes and their photochromic derivatives

Photochromic derivatives of 5-alkyl-2-(1,3,4-oxadiazol-2-yl)thiophenes have been synthesized for the first time. Their photochromic and fluorescent properties have been studied.