950186-11-5

Basic information

• Product Name: 3-(4-acetoxyphenyl)propanenitrile
• Synonyms: 3-(4-acetoxyphenyl)propanenitrile
• CAS NO: 950186-11-5
• Molecular Weight: 189.214
• Mol File: 950186-11-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-(4-acetoxyphenyl)propanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-acetoxyphenyl)propanenitrile(950186-11-5)
• EPA Substance Registry System: 3-(4-acetoxyphenyl)propanenitrile(950186-11-5)

Safety Data

• Hazardous Substances Data: 950186-11-5(Hazardous Substances Data)

Upstream product

• 91143-05-4 4-(3-oxopropyl)phenyl acetate 
• 2345-34-8 4-acetyloxy-benzoic acid 
• 107-13-1 acrylonitrile 
• 23838-70-2 3-(4-hydroxyphenyl)propanoic acid amide 
• 5597-50-2 3-(4-hydroxyphenyl)propionic acid methyl ester 
• 501-97-3 4-hydroxyphenylpropionic acid 
• 7249-16-3 3-(4-acetoxyphenyl)-propionic acid 
• 878-00-2 4-formylphenyl acetate 

Downstream Products

• 96169-02-7 Tetrahydroxanthohumol 
• 60-82-2 3-(4-Hydroxy-phenyl)-1-(2,4,6-trihydroxy-phenyl)-propan-1-on 
• 17362-17-3 3-(p-hydroxyphenyl)propiononitrile 
• 95283-30-0 2,6-Dihydroxy-4-methoxy-3-isoamyl--phenon 

Relevant articles and documents

Visible- And UV-Light-Induced Decarboxylative Radical Reactions of Benzoic Acids Using Organic Photoredox Catalysts

Photoinduced decarboxylative radical reactions of benzoic acids with electron-deficient alkenes, diborane, and acetonitrile under organic photoredox catalysis conditions and mild heating afforded adducts, arylboronate esters, and the reduction product, respectively. The reaction is thought to involve single-electron transfer promoted the generation of aryl radicals via decarboxylation. A diverse range of benzoic acids were found to be suitable substrates for this photoreaction. Only our two-molecule organic photoredox system can work well for the direct photoinduced decarboxylation of benzoic acids.

Titanium(III)-Catalyzed Reductive Decyanation of Geminal Dinitriles by a Non-Free-Radical Mechanism

A titanium-catalyzed mono-decyanation of geminal dinitriles is reported. The reaction proceeds under mild conditions, tolerates numerous functional groups, and can be applied to quaternary malononitriles. A corresponding desulfonylation is demonstrated as well. Mechanistic experiments support a catalyst-controlled cleavage without the formation of free radicals, which is in sharp contrast to traditional stoichiometric radical decyanations. The involvement of two TiIII species in the C?C cleavage is proposed, and the beneficial role of added ZnCl2 and 2,4,6-collidine hydrochloride is investigated.

A novel system for the synthesis of nitriles from aldehydes using aqueous ammonia and sodium dichloroiodate

A simple and mild method for the conversion of varieties of aldehydes to the corresponding nitriles using aqueous ammonia and aqueous sodium dichloroiodate reagent at room temperature is discussed. Advantages of this system are short reaction time, easy work-up and moderate to good yields.