95024-24-1

Upstream product

• 1628-29-1 10-acetyl-10H-phenothiazine 
• 98-88-4 benzoyl chloride 
• 2557-78-0 2-fluorothiophenol 
• 56107-02-9 4-chloro-3-nitrobenzophenone 
• 94-36-0 dibenzoyl peroxide 
• 19210-66-3 10-vinyl-10H-phenothiazine 
• 92-84-2 10H-phenothiazine 

Downstream Products

• 907547-06-2 (10-(4-(4-Methylpiperazin-1-yl)butyl)-10H-phenothiazin-2-yl)(phenyl)methanone 
• 109746-90-9 (10-methyl-10H-phenothiazin-2-yl)-phenyl-methanone 

Relevant academic research and scientific papers

UBIQUITIN-SPECIFIC PEPTIDASE 24 INHIBITOR, MEDICINAL COMPOSITION INCLUDING THE SAME AND METHOD OF DELAYING OR REVERSING MULTIDRUG RESISTANCE IN CANCERS USING THE SAME

The present invention relates to a ubiquitin-specific peptidase 24 inhibitor, a medicinal composition including the same and a method of delaying or reversing multidrug resistance in cancers using the same. The USP24 inhibitor, which includes a shUSP24 RNA and/or a carbonyl substituted phenyl compound, can serve as a chemosensitizing agent for inhibiting the drug pump out, cancer sternness and genomic instability of cancer cells, thereby being applied to a medicinal composition and a method for delaying or reversing multidrug resistance in cancers.