95041-53-5

Upstream product

• 51255-17-5 (2S,3R)-2-Hydroxymethyl-5-methoxy-tetrahydro-furan-3-ol 
• 533-67-5 2-deoxy-D-ribose 
• 51785-70-7 methyl 3,5-dibenzoyloxy-2-deoxy-β-D-erythropentofuranoside 
• 80339-59-9 methyl 3,5-dibenzoyloxy-2-deoxy-α-D-erythropentofuranoside 
• 51255-17-5 1-O-methyl-2-deoxy-D-ribofuranoside 
• 98-88-4 benzoyl chloride 
• 452-51-7 D-2-deoxyribose 
• 108647-88-7 ((2R,3S)-3-(benzoyloxy)-5-methoxytetrahydrofuran-2-yl)methyl benzoate 

Downstream Products

• 80311-45-1 C₂₃H₂₄O₇ 
• 80311-45-1 C₂₃H₂₄O₇ 
• 140186-59-0 methyl 2,3-di-O-benzyl-6-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-glucopyranoside 
• 140186-57-8 1,2:3,4-di-O-isopropylidene-5-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-galactopyranoside 
• 140186-58-9 1,2:5,6-di-O-isopropylidene-3-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-glucofuranoside 
• 140186-56-7 methyl 2,3-O-isopropylidene-5-O-(3,5-di-O-benzoyl-2-deoxy-α-D-ribofuranosyl)-α-D-ribofuranoside 
• 55734-51-5 1,4-anhydro-2-deoxy-3,5-di-O-benzoyl-D-erythro-pent-1-enitol 
• 35898-30-7 C₂₄H₂₂N₂O₇ 
• 51255-12-0 1-O-acetyl-3,5-di-O-benzoyl-2-deoxy-D-erythro-pentafuranose 
• 145417-01-2 2-pyridyl 3,5-di-O-benzoyl-2-deoxy-1-thio-α,β-D-ribofuranoside 

Relevant academic research and scientific papers

A mild and rapid glycosylation reaction between pyrimidine bases and 2-deoxyribofuranosyl N,N,N',N'-tetramethylphosphoroamidates

A trimethylsilyl triflate-mediated coupling reaction to produce protected 2′-deoxynucleosides has been developed by using N,N,N',N'-tetramethylphosphoroamidate as a leaving group. In this reaction, employment of a 3,4,5-trimethoxybenzoyl group as the 3-hydroxyl protective group in the sugar moiety improved the β-stereoselectivity via a novel 1,3-participation.

Stereoselective synthesis of α-linked 2-deoxysaccharides and furanosaccharides by the use of 2-deoxy 2-pyridyl-1-thio pyrano- and furanosides as donors and methyl iodide as an activator

A practical and highly stereoselective glycosidation methodology is described, where anomeric mixture of 2-deoxy 2-pyridyl-1-thiopyranoside donors (1-3,27) have been coupled with several sugar alcohols (4-8,29,31) on activation by methyl iodide to obtain axially linked 2-deoxysaccharides (9-17,30,32,33). Application of this method for the synthesis of disaccharide fragment 28 of avermectin is also described. Utility of this method is also shown by use of 2-pyridyl-1-thiofuranosides (34-36) as donors to prepare α-linked furanosides (42-51).

Improved procedure for the regiospecific synthesis of 2'-deoxyribonucleosides

2'-Deoxyribonucleosides are regiospecifically synthesized in high yields by catalyzing with KI-dibenzo-18-crown-6 PTC the condensation between unprotected silylated purines and pyrimidines and the appropriate easily available 2-deoxy-ribofuranosyl or pyranosyl sugar derivatives.

5(S), 6(R)-5, 7-DIBENZOYLOXY-6-HYDROXYHEPTANOATE ESTER : IMPROVED SYNTHESIS OF A LEUKOTRIENE INTERMEDIATE

The title compound, a key intermediate in the synthesis of leukotriene A4, was prepared by a convenient procedure from 2-deoxy-D-ribose.