95123-16-3

Basic information

• Product Name: 1-Decen-3-one, 1-phenyl-, (E)-
• CAS NO: 95123-16-3
• Molecular Formula: C16H22O
• Molecular Weight: 230.35
• Mol File: 95123-16-3.mol

Chemical Properties

• CAS DataBase Reference: 1-Decen-3-one, 1-phenyl-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Decen-3-one, 1-phenyl-, (E)-(95123-16-3)
• EPA Substance Registry System: 1-Decen-3-one, 1-phenyl-, (E)-(95123-16-3)

Safety Data

• Hazardous Substances Data: 95123-16-3(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 111-64-8 n-octanoic acid chloride 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 821-55-6 2-Nonanone 
• 100-52-7 benzaldehyde 

Downstream Products

• 124745-48-8 (E)-1-phenyl-1-decen-3-ol 

Relevant articles and documents

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Chagas’ disease is a parasitic infection caused by Trypanosoma cruzi that is still treated by old and toxic drugs. In the search for novel alternatives, natural sources are an important source for new drug prototypes against T. cruzi to further structural

Acylation of Alkenes with the Aid of AlCl3 and 2,6-Dibromopyridine

Friedel-Crafts-type acylation of alkenes with acyl chlorides has been successfully conducted with a wide substrate scope by the combined use of AlCl3 and 2,6-dibromopyridine. Trisubstituted alkenes afford allylketones or vinylketones depending on the presence or absence of hydrogen atom(s) at the β-position to the acylation site, while monosubstituted alkenes exclusively afford vinylketones.

Metallic Nickel-Mediated Synthesis of Ketones by the Reaction of Benzylic, Allylic, Vinylic, and Pentafluorophenyl Halides with Acid Halides

Metallic nickel was investigated as a convenient coupling reagent for the synthesis of ketones by the reaction of benzylic, allylic, vinylic, and pentafluorophenyl halides with acid halides at 85 deg C in glyme.A variety of benzylic ketones with functional groups including halogen, cyano, methoxycarbonyl, and hydroxycarbonyl groups were prepared in good yields by this method.The reaction was demonstrated to proceed via organonickel halide intermediates formed by the smooth oxidative addition of benzylic and acyl halides to metallic nickel, which were trapped with electron-deficient olefins. (?-Allyl)nickel halides, prepared in situ at 85 deg C from allylic halides and the nickel, also worked for the preparation of ketones.Vinylic and pentafluorophenyl halides but not alkyl halides reacted with acid halides to give the corresponding ketones in moderate yields.