95452-96-3

Upstream product

• 95452-95-2 (E)-(3S,4S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-phenyl-pent-1-en-3-ol 
• 74-88-4 methyl iodide 
• 85199-60-6 (R-(R^*,R^*))-β-hydroxy-α-methyl-2-furanpropanoate 
• 86838-36-0 (2R,3S)-3-hydroxy-2-methyl-5-phenyl-pent-4-enoic acid ethyl ester 
• 90545-69-0 (1R,2S)-1-(furan-2-yl)-2-methylpropane-1,3-diol 
• 1449-46-3 benzyltriphenylphosphonium bromide 
• 95585-63-0 (2S,3S)-1,3-dihydroxy-2-methyl-5-phenyl-4-pentene 
• 86838-34-8 ethyl 2-methyl-3-oxo-5-phenylpent-4-enoate 

Downstream Products

• 88088-56-6 (E)-(3S,4R)-4-Methoxy-3-methyl-6-phenyl-hex-5-enoic acid 
• 73341-71-6 (-)-oudemanisin A 
• 88644-08-0 (3S,4R,E)-methyl 4-methoxy-3-methyl-6-phenylhex-5-enoate 
• 90664-08-7 (E)-(3S,4S)-2-Formyl-4-methoxy-3-methyl-6-phenyl-hex-5-enoic acid methyl ester 

Relevant academic research and scientific papers

THE USE OF A VERSATILE BUILDING BLOCK HAVING TWO CHIRAL CENTERS A TOTAL SYNTHESIS OF (-)-OUDEMANSIN

(-)-Oudemansin (4) has been synthesized from the chiral synthon 2 obtained by microbiological asymmetric reduction of the prochiral β-keto ester 1.Keywords - total synthesis; antibiotic; cleavage of furan; α-methyl β-hydroxy ester

THE ABSOLUTE CONFIGURATION OF OUDEMANSIN. TOTAL SYNTHESIS OF (-)-OUDEMANSIN.

(-)-Oudemansin (1) was synthesized from the optically active intermediate 10 obtained by microbiological asymmetric reduction of β-keto ester 3.Oudemansin was found to have the 9S, 10S absolute configuration.