95585-63-0

Upstream product

• 14371-10-9 (E)-3-phenylpropenal 
• 67498-12-8 (E)-(2S,3S)-3-Hydroxy-2-methyl-5-phenyl-pent-4-enoic acid methyl ester 
• 86853-06-7 Methyl 2-methyl-3-oxo-5-phenyl-4-pentenoate 
• 67498-12-8 (E)-syn-methyl 3-hydroxy-2-methyl-5-phenyl-4-pentanoate 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 86838-34-8 ethyl 2-methyl-3-oxo-5-phenylpent-4-enoate 
• 1009061-76-0 C₂₂H₂₁NO₂S₂ 
• 86838-36-0 (2R,3S)-3-hydroxy-2-methyl-5-phenyl-pent-4-enoic acid ethyl ester 

Downstream Products

• 73341-71-6 (-)-oudemanisin A 
• 88644-08-0 (3S,4R,E)-methyl 4-methoxy-3-methyl-6-phenylhex-5-enoate 
• 88088-56-6 (E)-(3S,4R)-4-Methoxy-3-methyl-6-phenyl-hex-5-enoic acid 
• 90664-08-7 (E)-(3S,4S)-2-Formyl-4-methoxy-3-methyl-6-phenyl-hex-5-enoic acid methyl ester 
• 95452-96-3 tert-Butyl-((E)-(2S,3S)-3-methoxy-2-methyl-5-phenyl-pent-4-enyloxy)-dimethyl-silane 
• 869385-07-9 (12R,13S,E)-tert-butyl 12-benzyloxy-2,2,13,23,23-pentamethyl-9,15,21-trioxo-3,3-diphenyl-4,22-dioxa-20-aza-3-silatetracos-10-ene-16-carboxylate 
• 869385-10-4 (1R,2S,3R,4S)-tert-butyl 3-benzyloxy-2-(6-(tert-butyldiphenylsilyloxy)-2-oxohexyl)-1-(2-cyanoethyl)-4-methyl-6-oxocyclohexanecarboxylate 
• 869385-14-8 (4aR,5S,6R,7S)-tert-butyl 6-benzyloxy-5-(6-(tert-butyldiphenylsilyloxy)-2-oxohexyl)-7-methyl-2,3,4,4a,5,6,7,8-octahydroquinoline-4a-carboxylate 
• 869385-08-0 (5S,6R,E)-tert-butyl 6-benzyloxy-13-(tert-butyldiphenylsilyloxy)-5-methyl-3,9-dioxotridec-7-enoate 

Relevant academic research and scientific papers

Diastereoselective synthesis of an advanced intermediate of the crocacin family using asymmetric transfer hydrogenation-DKR and Marshall allenylation as key reactions

The natural product of a crocacin-family structural scaffold bearing consecutive anti-anti-syn stereogenic centers was accomplished by means of ATH-DKR and Marshall allenylation reactions with high stereo-control levels. The salient feature of this process is that a single catalytic asymmetric Ru-complex was used for the chirality genesis of pivotal reactions with a high substrate-to-catalyst ratio.

Indene-based thiazolidinethione chiral auxiliary for propionate and acetate aldol additions

An indene-based thiazolidinethione chiral auxiliary was prepared in two steps from trans-1-amino-2-indanol. Chlorotitanium enolates of this chiral auxiliary delivered excellent diastereoselectivities in propionate and acetate aldol additions. The chiral a

Polycyclic molecules from linear precursors: Stereoselective synthesis of clavolonine and related complex structures

(Chemical Equation Presented) A clever way to clavolonine: The total synthesis of the lycopodium alkaloid clavolonine (2) from a linear precursor 1 that contains the complete 16-carbon-atom chain is reported (see scheme). Intramolecular and transannular c

STEREOSELECTIVE ADDITIONS TO CARBOXYLIC ACID DIANIONS AND β-LACTONE SUBSTITUTED ESTER ENOLATES. APPLICATION TO THE SYNTHESIS OF RACEMIC EPI-BLASTMYCINONE, δ-MULTISTRIATINE, PARACONIC ESTERS AND LIGNANTYPE DILACTONES

New stereoselective syntheses are reported for racemic 4-epi-blastmycinone (6) and δ-multistriatine (13) utilizing the anti-configurated γ,δ-unsaturated β-hydroxy-carboxylic acids 2a/b.A diastereo- and enantioselective aldoltype addition of phenylacetic acid dianion to benzaldehyde has been achaived by employing optically active alkoxide amide bases.Finally, highly stereocontrolled additions to the novel β-lactone substituted ester enolates 22 are described.

THE ABSOLUTE CONFIGURATION OF OUDEMANSIN. TOTAL SYNTHESIS OF (-)-OUDEMANSIN.

(-)-Oudemansin (1) was synthesized from the optically active intermediate 10 obtained by microbiological asymmetric reduction of β-keto ester 3.Oudemansin was found to have the 9S, 10S absolute configuration.