86838-34-8

Upstream product

• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 100-52-7 benzaldehyde 
• 105-37-3 Ethyl propionate 
• 14371-10-9 (E)-3-phenylpropenal 

Downstream Products

• 122571-57-7 2,4-dimethyl-4-(ethoxycarbonyl)-3-(2-phenylethyl)cyclohexan-1-one 
• 122571-54-4 4,6-Dimethyl-5-phenethyl-2-oxa-bicyclo[2.2.2]octan-3-one 
• 73341-71-6 (-)-oudemanisin A 
• 88644-08-0 (3S,4R,E)-methyl 4-methoxy-3-methyl-6-phenylhex-5-enoate 
• 88088-56-6 (E)-(3S,4R)-4-Methoxy-3-methyl-6-phenyl-hex-5-enoic acid 
• 95585-63-0 (2S,3S)-1,3-dihydroxy-2-methyl-5-phenyl-4-pentene 
• 90664-08-7 (E)-(3S,4S)-2-Formyl-4-methoxy-3-methyl-6-phenyl-hex-5-enoic acid methyl ester 
• 95452-96-3 tert-Butyl-((E)-(2S,3S)-3-methoxy-2-methyl-5-phenyl-pent-4-enyloxy)-dimethyl-silane 
• 95452-95-2 (E)-(3S,4S)-5-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-1-phenyl-pent-1-en-3-ol 
• 86838-36-0 (2R,3S)-3-hydroxy-2-methyl-5-phenyl-pent-4-enoic acid ethyl ester 
• 86838-36-0 (2S,3S,E)-ethyl 3-hydroxy-2-methyl-5-phenylpent-4-enoate 
• 122571-53-3 2,4-dimethyl-4-(ethoxycarbonyl)-3-(2-phenylethenyl)-cyclohex-2-en-1-one 
• 122571-52-2 2-(ethoxycarbonyl)-2-methyl-5-phenyl-4-propionylcyclohexan-1-one 

Relevant academic research and scientific papers

Stereoselective reduction of 2-methyl-3-oxo esters (or amides) with sodium borohydride catalyzed by manganese (II) chloride or tetrabutylammonium borohydride. A practical preparation of erythro and threo-3-hydroxy-2-methyl esters (or amides)

erythro-3-Hydroxy-2-methylpropionates or erythro-3-hydroxy-2-methylpropionamides were prepared with high stereoselectivity by NaBH4 reduction of the corresponding 2-methyl-3-oxo esters or 2-methyl-3-oxo amides in the presence of a catalytic amount of manganese(II) chloride. On the other hand, reduction of these substrates with n-Bu4NBH4 provided threo-isomers selectively. erythro-Selective reduction of 2-methyl-3-oxo amides with NaBH3CN in 1N HCl-MeOH is also described.