95679-57-5

Upstream product

• 54680-53-4 3-oxo-5-phenylpentanoic acid 
• 75-65-0 tert-butyl alcohol 
• 501-52-0 3-Phenylpropionic acid 
• 2033-24-1 cycl-isopropylidene malonate 
• 645-45-4 hydrocinnamic acid chloride 
• 1694-31-1 tert-butyl acetoacetate 
• 100-39-0 benzyl bromide 
• 1207973-75-8 lithium tert-butyl acetate 

Downstream Products

• 199525-61-6 2-(3-Phenyl-propionyl)-succinic acid 1-tert-butyl ester 4-ethyl ester 
• 1431726-54-3 (1R,5S,8R)-tert-butyl 8-benzyl-7-hydroxy-2-(4-methylphenylsulfonyl)-2-azabicyclo[3.3.1]non-6-ene-6-carboxylate 
• 1431726-55-4 C₂₇H₃₃NO₅S 
• 1381800-56-1 C₁₆H₂₂O₃ 
• 1381800-73-2 t-butyl 2-chloro-2-methyl-3-oxo-5-phenylpentanoate 
• 133271-03-1 (R)-3-Hydroxy-5-phenyl-pentanal 
• 133271-09-7 C₁₁H₁₄O₂ 
• 1313532-25-0 5-tert-butyl 3-ethyl 4-phenethyl-1H-pyrazole-3,5-dicarboxylate 
• 1313532-91-0 (Z)-tert-butyl 5-phenyl-3-(((trifluoromethyl)sulfonyl)oxy)pent-2-enoate 
• 199525-67-2 2-Fluoro-2-(3-phenyl-propionyl)-succinic acid 1-tert-butyl ester 4-ethyl ester 

Relevant academic research and scientific papers

Phase-Transfer Catalyzed Asymmetric [4 + 1] Annulations for the Synthesis of Chiral 2,2-Disubstituted Tetrahydrothiophenes

An efficient catalytic asymmetric [4 + 1] reaction, which features the use of simple β-keto esters as one-carbon nucleophiles and 5-succinimidothio-pent-2-enoates as four-atom bielectrophiles, has been developed in the presence of a bifunctional chiral ph

Oxone-promoted hydration of electron-deficient allenic esters and ketones into 1,3-dicarbonyl compounds

Abstract A novel and mild protocol for the hydration of electron-deficient allenic esters and ketones into various 1,3-dicarbonyl compounds is described. The hydration of allenes promoted by oxone in DMF afforded the corresponding products in moderate to good yields. This work features the employment of only a catalytic amount of inexpensive and nontoxic solid reagent oxone (2KHSO5·KHSO4·K2SO4), avoiding the utility of toxic metals or traditional Br?nsted acids, in a green version of viewpoint. A possible reaction mechanism for this transformation is also primarily proposed.

Organocatalyzed asymmetric synthesis of morphans

A general effective organocatalyzed synthesis of enantioenriched morphans with up to 92% ee was developed. The morphan scaffold was constructed in a one-pot tandem asymmetric organocatalyzed Michael addition followed by a domino Robinson annulation/aza-Michael intramolecular reaction sequence from easily available starting materials.

Chemoselective, Regioselective, and E/Z-Diastereoselective Synthesis of 2-Alkylidenetetrahydrofurans by Sequential Reactions of Ambident Dianions and Monoanions

A number of novel β-ketoesters were prepared by regioselective alkylation reactions of simple β-ketoester dianions. The cyclization of the dianions of these 1,3-dicarbonyl derivatives with 1-bromo-2-chloroethane afforded a variety of 2-alkylidenetetrahydr

A short, efficient synthesis of monofluoro ketomethylene peptide isostere core units

Monofluoro ketomethylene peptide isosteres can be prepared by a four step sequence from carboxylic acids in satisfactory overall yields (30-60%). Fluorine is introduced by electrophilic fluorination of a β-ketoester enolate with SelectFluor(TM).