959-30-8

Basic information

• Product Name: [(amino-phenyl-methylidene)amino] benzoate
• CAS NO: 959-30-8
• Molecular Formula: C₁₄H₁₂N₂O₂
• Molecular Weight: 240.261
• Mol File: 959-30-8.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 390.3°Cat760mmHg
• Flash Point: 189.9°C
• Density: 1.16g/cm³
• CAS DataBase Reference: [(amino-phenyl-methylidene)amino] benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: [(amino-phenyl-methylidene)amino] benzoate(959-30-8)
• EPA Substance Registry System: [(amino-phenyl-methylidene)amino] benzoate(959-30-8)

Safety Data

• Hazardous Substances Data: 959-30-8(Hazardous Substances Data)

Usage

General Description

The chemical compound [(amino-phenyl-methylidene)amino] benzoate is an organic compound that consists of a benzene ring attached to a carboxylate group and an amino group. It is commonly used in the field of organic chemistry and pharmaceuticals due to its potential pharmacological properties. [(amino-phenyl-methylidene)amino] benzoate has been studied for its potential biological activities, including anti-inflammatory and antioxidant effects. Additionally, [(amino-phenyl-methylidene)amino] benzoate has been investigated for its potential use in the synthesis of novel organic compounds with pharmaceutical applications. Its chemical structure and properties make it a subject of interest for researchers looking to develop new medications or materials with specific biological activities.

Upstream product

• 98-88-4 benzoyl chloride 
• 613-92-3 N-hydroxybenzenecarboximidamide 
• 613-92-3 N-hydroxyl-benzamidine 
• 100-47-0 benzonitrile 
• 65-85-0 benzoic acid 
• 29577-09-1 O-benzoylbenzenehydroximidoyl chloride 
• 613-92-3 (E)-N'-hydroxybenzimidamide 

Downstream Products

• 959-32-0 N-(benzoyloxy)benzamide 
• 5585-14-8 3,4-diphenyl-furazan 2-oxide 
• 888-71-1 3,5-diphenyl-1,2,4-oxadiazole 
• 7732-18-5 water 
• 93-58-3 benzoic acid methyl ester 
• 100-47-0 benzonitrile 
• 65573-12-8 4-chloro-5H-1,2,3-dithiazole-5-one 
• 180723-56-2 5-Cyano-3-phenyl-1,2,4-thidiazole-4-oxide 
• 613-92-3 N-hydroxyl-benzamidine 
• 65-85-0 benzoic acid 

Relevant articles and documents

Three N2-benzoyloxybenzamidines: Sheet structures built from hard and soft hydrogen bonds and aromatic π-π stacking interactions

The molecular structures of N2-(benzoyloxy)benzamidine, (I), N2-(2-hydroxybenzoloxy)benzamidine, (II), and N 2-benzoyloxy-2-hydroxy-benzamidine, (III), were analyzed. The molecules of (I) were linked into chains by a single N-H···N hydrogen bond and these chains were linked into sheets by aromatic π-π stacking interactions. The molecules of (I) and (III) had chain extended conformations, with the aryl groups remote from one another. It was observed that in these three compounds conformations were influenced by intermolecular hydrogen bonding involving the substituted aryl rings.

Formation and cyclization of N′-(benzoyloxy)benzenecarboximidamides

The formation of N′-(benzoyloxy)benzenecarboximidamides and their subsequent cyclization to 3,5-disubstituted 1,2,4-oxadiazoles in different solvents were studied. A probable reaction mechanism was proposed on the basis of the obtained results.

NOVEL O-ACYLOXIME DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE

The present invention relates to novel O-acyloxime derivatives, a preparation method thereof and a pharmaceutical composition comprising the same for prevention and treatment of cardiovascular disease. The O-acyloxime derivatives according to the present invention may valuably be used for prevention and treatment of cardiovascular diseases such as hyperlipidemia, coronary arterial heart disease, atherosclerosis, and myocardial infarction caused by Lp-PLA2, because they have excellent inhibitory effect of Lp-PLA2.