96562-58-2Relevant articles and documents
Method for preparing (R)-(+)-2-(4-hydroxyphenoxy) methyl propionate
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Paragraph 0049-0050, (2021/04/26)
The invention provides a method for preparing (R)-(+)-2-(4-hydroxyphenoxy) methyl propionate, and belongs to the technical field of preparation of pesticide intermediates. The method for preparing (R)-(+)-2-(4-hydroxyphenoxy) methyl propionate comprises the following steps: mixing halogenated methyl propionate, hydroquinone, an alkaline reagent and a polar aprotic solvent, and carrying out condensation reaction to obtain (R)-(+)-2-(4-hydroxyphenoxy) methyl propionate, wherein the halogenated methyl propionate is (S)-(-)-methyl-2-chloropropionate), (S)-(-)-methyl-2-bromopropionate or (S)-(-)-methyl-2-iodopropionate. According to the method, hydroquinone and halogenated methyl propionate are taken as raw materials, (R)-(+)-2-(4-hydroxyphenoxy) methyl propionate (MAQ) is synthesized in a polar aprotic solvent system through a one-step method, the process is simple, environment friendliness is achieved, the product quality is good, and the yield is high.
Preparation method of R-(+)-2-[4-(hydroxyphenoxy) propionate
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Paragraph 0029; 0030; 0031; 0032; 0033; 0034, (2017/06/02)
The invention discloses a preparation method of a herbicide intermediate R-(+)-2-[4-(hydroxyphenoxy) propionate by using a novel solid acid catalyst. The method improves the traditional esterification process, reduces the discharge of wastewater, and plays great improvement role in preventing the inversion of configuration of a chiral product.
Preparation of mixtures of (R)- and (S)-2-(4-alkanoylphenoxy)- or (R)- and (S)-2-(4-aroylphenoxy)propionic esters
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, (2008/06/13)
A mixture of (R)- and (S)-2-(4-alkanoylphenoxy)- or (R)- and (S)-2-(4-aroylphenoxy)propionic esters I STR1 with an enantiomeric excess of at least 90% is prepared by reacting a mixture of (R) and (S) enantiomer of a 2-phenoxypropionic ester II STR2 in which the appropriate (R) or (S) isomer is present in excess, with a carboxylic acid derivative of the formula III (X=OH, halogen, R1 COO or sulfonyloxy) in the presence of a Friedel-Crafts catalyst. The (R)- or (S)-2-(4-alkanoylphenoxy)propionic esters and (R)- or (S)-2-(4-hydroxyphenoxy)propionic esters are used for preparing crop protection agents and drugs.