970-31-0Relevant academic research and scientific papers
Copper(ii)-catalyzed coupling reaction: An efficient and regioselective approach to N′,N′-diaryl acylhydrazines
Zhang, Ji-Quan,Huang, Gong-Bin,Weng, Jiang,Lu, Gui,Chan, Albert S. C.
, p. 2055 - 2063 (2015/03/05)
Using N′-aryl acylhydrazines as aryl donors, a novel copper(ii)-catalyzed homo-coupling reaction of N′-aryl acylhydrazines has been developed for the synthesis of N′,N′-diaryl acylhydrazines. We also provided a complementary procedure for the preparation of unsymmetrical diaryl acylhydrazines via cross-coupling reaction. These protocols featured mild reaction conditions, wide functional group tolerance and highly regioselective products. Control experiments indicated that this kind of coupling reaction might undergo a transient acyl diazene intermediate. This journal is
KOt-Bu promoted homocoupling and decomposition of N'-aryl acylhydrazines: synthesis of unsymmetric N',N'-diaryl acylhydrazines
Wang, Wei-Juan,Zhang, Ting,Duan, Li-Jun,Zhang, Xue-Jing,Yan, Ming
, p. 9073 - 9080 (2015/11/09)
The KOt-Bu promoted homocoupling and decomposition of N'-aryl acylhydrazines has been achieved. The method allows for a novel and efficient synthesis of unsymmetric N',N'-diaryl acylhydrazines under mild reaction conditions. The reaction probably proceeds via the generation of N'-centered acylhydrazine radicals and the subsequent homolytic aromatic substitution.
An oxidative transformation of N′-phenylhydrazide to t-butyl ester using a copper(II) halide-lithium t-butoxide system
Yamaguchi, Jun-Ichi,Aoyagi, Takashi,Fujikura, Ryohei,Suyama, Takayuki
, p. 466 - 467 (2007/10/03)
Reactions of hydrazides or N1-phenylhydrazides with a copper(II) reagent prepared from copper(II) bromide and lithium t-butoxide smoothly proceeded to give the corresponding t-butyl ester in high yield.
Reduction of Ag(I) by 1-acyl-2-arylhydrazines: Mechanism of photographic infectious development
Bowman, W. Russell,Forshaw, J. Anthony,Hall, Kevin P.,Kitchin, Jonathan P.,Mott, Andrew W.
, p. 3961 - 3972 (2007/10/03)
The photographic process of 'infectious development' in which 1-acyl-2-arylhydrazines reduce Ag(I) has been studied using analogues. 1-Acyl-2-aryldiazenes, resulting from oxidation of 1-acyl-2-arylhydrazines, are hydrolysed to anions of aryldiazenes (ArN = NH), which undergo further oxidation with loss of nitrogen to yield aryl radicals. The aryl radicals cause 'feedback inhibition' which is prevented by the addition of benzhydrol.
