97118-97-3Relevant academic research and scientific papers
Synthesis of fully-substituted pyridines and dihydropyridines in a highly chemoselective manner utilizing a multicomponent reaction (MCR) strategy
Sarkar, Satavisha,Das, Deb K.,Khan, Abu T.
, p. 53752 - 53760 (2015/02/18)
An efficient protocol has been developed for the synthesis of pyridines and 1,4-dihydropyridines based on chemoselective multicomponent reactions. Using readily available aldehydes, malononitrile and primary aliphatic amines, this procedure provides a divergent but straightforward access to a wide range of fully substituted pyridines and dihydropyridines via a primary amine based chemoselective strategy. Simple reaction procedure, good yields, mild reaction conditions, applicabilility to a wide range of substrates with the aid of chemoselectivity make this present protocol more innovative than existing ones. This journal is
Synthesis and pharmacological activity of some nitrofuraldehyde cyanopyridine derivatives
Castedo,Quintela,Riguera
, p. 555 - 557 (2007/10/02)
Compounds 3a-f were obtained by condensing 5-nitrofuraldehyde hydrazone with five iminoethers derived from the 6-alkoxy-(or alkylamino-)2-amino-4-aryl-3,5-dicyanopyridines. Tests of their antimicrobial activity against 16 micro-organisms showed that 3a (R
