97799-86-5

Basic information

• Product Name: 1H-Indole, 1,2,4,6-tetramethyl-
• CAS NO: 97799-86-5
• Molecular Formula: C12H15N
• Molecular Weight: 173.258
• Mol File: 97799-86-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1,2,4,6-tetramethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1,2,4,6-tetramethyl-(97799-86-5)
• EPA Substance Registry System: 1H-Indole, 1,2,4,6-tetramethyl-(97799-86-5)

Safety Data

• Hazardous Substances Data: 97799-86-5(Hazardous Substances Data)

Usage

Structure

A six-membered benzene ring fused to a five-membered nitrogen-containing ring

Appearance

Colorless to light yellow liquid

Odor

Strong, sweet, floral

Usage

Production of fragrances and perfumes, synthesis of pharmaceuticals and other organic compounds

Biological activities

Potential anti-inflammatory and anti-proliferative properties

Upstream product

• 65081-41-6 1,2,4,6-tetramethyl-3-nitropyridinium iodide 
• 75815-80-4 (1S)-N-(1-methylethylidene)-1-phenylethylamine 
• 67-64-1 acetone 
• 618-36-0 rac-methylbenzylamine 
• 124-30-1 1-aminooctadecane 
• 109-89-7 diethylamine 
• 124-40-3 dimethyl amine 
• 6407-34-7 methyl-1 ethylideneamine 
• 110-89-4 piperidine 

Downstream Products

• 1293366-63-8 3-(4-methoxyphenyl)-1,2,4,6-tetramethylindole 

Relevant articles and documents

SYNTHESIS OF INDOLES FROM PYRIDINIUM SALTS. 3. ORIGIN OF NITROGEN IN THE INDOLE MOLECULE IN SYNTHESIS FROM 3-NITROPYRIDINIUM SALT

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Indoles from 3-Nitropyridinium Salts: A new Route to Chiral Indoles and Indolines

(S)-1-(1-Methylbenzyl)-2,4,6-trimethylindole was prepared by interaction of (S)-isopropyliden(1-methylbenzyl)amine with 1,2,4,6-tetramethyl-3-nitropyridinium iodide.The indoles thus prepared undergo diastereoselective hydride reduction and debenzylation to afford chiral (S)-2,4,6-trimethylindoline with high yield an optical purity up to 76percent.

Synthesis of indoles from pyridinium salts. 7. Sterically hindered alkyl-3-nitropyridinium salts in the synthesis of indoles

The introduction of bulky alkyl substituents (iso-Pr,tert-Bu) into any positions of the starting 3-nitropyridinium salt only increases the reaction time and decreases the yields of the corresponding alkylindoles somewhat.

FORMATION OF 6-NITRODIHYDRO- AND 6-NITROTETRAHYDROQUINOLINES. ANOTHER REACTION OF 3-NITROPYRIDINIUM SALTS WITH N-METHYLACETONIMINE

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