98018-68-9Relevant academic research and scientific papers
Copper-Catalyzed One-Pot Synthesis of Dibenzofurans, Xanthenes, and Xanthones from Cyclic Diphenyl Iodoniums
Zhu, Daqian,Li, Min,Wu, Zhouming,Du, Yongliang,Luo, Bingling,Huang, Peng,Wen, Shijun
, p. 4566 - 4571 (2019/07/09)
Oxygenation of cyclic diphenyl iodoniums (CDPIs) with varied medium-ring sizes has been fully investigated. This practical copper-catalyzed tandem reaction of CDPIs with water as the oxygen source enables the construction of derivatised dibenzofurans and xanthenes at moderate to good yields. Moreover, structurally important xanthones are also successfully accessed under the oxygenation conditions with additional TEMPO.
CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF
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, (2008/06/13)
The present invention relates to a cytokine production inhibitor comprising a compound of the formula [I] wherein R1is aryl or heteroaryl; B is a group of the formula (a) or (b) wherein R2is hydrogen atom, hydroxy, halogen atom and t
Therapeutic agent for osteoporosis and triazepine compound
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, (2008/06/13)
Therapeutic agents for osteoporosis comprising, as an active ingredient, a triazepine compound of the formula ?I! STR1 wherein R1 is aryl or heteroaryl; R2 is hydrogen atom, hydroxy, halogen atom or lower alkyl; R4 is hydrogen atom or halogen atom, or R2 and R4 form carbonyl combinedly together with the carbon atom to which they bond; R3 is hydrogen atom, lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, --X--Y wherein X is --(CH2)m --, --CO--, --COCH2 --, --NH--, --NHCH2 --, --CH2 NH--, --CH2 NHCO--, --OCH2 --, --(CH2)n O-- or --CH2 S-- and Y is halogen atom, cycloallyl, aryl or heteroaryl; and A is benzene ring or thiophene ring, or a salt thereof, novel triazepine compounds, and intermediate triazepine compounds for producing these triazepine compounds. The triazepine compounds of the formula ?I! have superior bone resorption-inhibitory action and are useful as therapeutic agents for osteoporosis.
