Enantiomeric effects of homologues of disoxaril on the inhibitory activity against human rhinovirus-14

DOI: 10.1021/jm00398a009

Source and publish data:

Journal of Medicinal Chemistry p. 540 - 544 (1988)

Update date:2022-08-05

Topics:

Authors:

Diana Diana

Otto Otto

Treasurywala

McKinlay

Oglesby Oglesby

Maliski Maliski

Rossmann

Smith Smith

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Article abstract of DOI:10.1021/jm00398a009

X-ray crystallography studies of racemic 5-[7-[4-(4,5-dihydro-4-methyl-2-oxazolyl)phenoxy]heptyl]-3-methyl isoxazole (2) bound to human rhinovirus-14 (HRV-14) indicate selective binding of the S isomer. This result correlates well with the 10-fold greater

Full text of DOI:10.1021/jm00398a009

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