98369-79-0Relevant academic research and scientific papers
Photocatalytic carbanion generation from C-H bonds-reductant free Barbier/Grignard-type reactions
Berger, Anna Lucia,Donabauer, Karsten,K?nig, Burkhard
, p. 10991 - 10996 (2019/12/28)
We report a redox-neutral method for the generation of carbanions from benzylic C-H bonds in a photocatalytic Grignard-type reaction. The combination of photo- and hydrogen atom transfer (HAT) catalysis enables the abstraction of a benzylic hydrogen atom, generating a radical intermediate. This radical is reduced in situ by the organic photocatalyst to a carbanion, which is able to react with electrophiles such as aldehydes or ketones, yielding homobenzylic secondary and tertiary alcohols.
Diastereoselective and Enantioselective Conjunctive Cross-Coupling Enabled by Boron Ligand Design
Myhill, Jesse A.,Wilhelmsen, Christopher A.,Zhang, Liang,Morken, James P.
, p. 15181 - 15185 (2018/11/30)
Enantio- and diastereoselective conjunctive cross-coupling of β-substituted alkenylboron "ate" complexes is studied. Whereas β-substitution shifts the chemoselectivity of the catalytic reaction in favor of the Suzuki-Miyaura product, use of a boronic este
NOVEL SYNTHESIS OF BENZYLLITHIUMS FROM BENZYLSELENIDES
Clarembeau, M.,Krief, A.
, p. 1093 - 1096 (2007/10/02)
Benzylselenides are found to be valuable precursors of benzyllithiums.The scope of the new method is disclosed.
