98488-57-4

Upstream product

• 700-75-4 2-methoxy-N,N-dimethyl-benzenamine 
• 13661-34-2 1,2-dimethoxy-3,5-dinitrobenzene 
• 74-89-5 methylamine 
• 7539-25-5 1-methoxy-2,3,5-trinitrobenzene 
• 108-95-2 phenol 
• 67-56-1 methanol 
• 16400-29-6 N-methyl-2',4',6'-trinitroacetanilide 
• 7697-37-2 nitric acid 
• 860734-45-8 4-methoxy-2,3,6-trinitro-aniline 
• 860578-25-2 acetic acid-(4-methoxy-2,3,6-trinitro-anilide) 
• 10541-78-3 2-methoxy-N-methylaniline 
• 858005-55-7 1,5-dinitro-2-(toluene-4-sulfonylamino)-3-(toluene-4-sulfonyloxy)-benzene 
• 859490-67-8 toluene-4-sulfonic acid-(2-hydroxy-4,6-dinitro-anilide) 
• 5327-44-6 3,5-dinitroanisole 

Downstream Products

• 118449-72-2 N-methyl-2'-methoxy-4',6'-dinitroacetanilide 
• 106652-41-9 2-methoxy-N-methyl-4,6,N-trinitro-aniline 

Relevant academic research and scientific papers

Pd(OAc)2-catalyzed dinitration reaction of aromatic amines

Taking advantage of Pd(OAc)2-catalyzed dinitration reactions with Bi(NO3)3·5H2O in trifluoroethanol (TFE) and trifluoroacetic acid (TFA), we have developed an efficient and practical method for the synthesis of secondary dinitro-aromatic amines. The products could be applied to the preparation of 5-amine-N-methyl-benzimidazolone, the azo-dyes, economic advantages. The method has also been expanded to the dinitration reaction of some tertiary aromatic amines.

Electrophilic nitration of electron-rich acetophenones

It is demonstrated that electron-rich disubstituted acetophenones react according to various electrophilic nitration conditions that generally lead to ipso substitution accompanying the conventional reaction. The hydroxy substituent does not seem prone to

Kinetics of the Reactions of Nitro-substituted N-Alkylacetanilides with Sodium Methoxide in Methanol

The sodium methoxide-catalysed methanolysis of N-ethyl (3) or N-methyl-2',4',6'-trinitroacetanilide (4) is found to proceed with initial formation of a 1,3-disubstituted anionic ?-complex (II), which then reverts to the reactant system, relatively slowly giving N-alkyl-4-methoxy-(main product) and N-alkyl-2'-methoxy-4',6'-dinitroacetanilides with the amido group unchanged, via a 1,4-disubstituted anionic ?-complex (III); kinetics and absorption and 1H n.m.r. spectral data are reported.