98555-51-2

Basic information

• Product Name: DIMETHYL 5-BROMOPYRIDINE-2,3-DICARBOXYLATE
• Synonyms: 5-Bromopyridine-2,3-dicarboxylic acid;5-BroMo-2,3-pyridinedicarboxylic acid;5-bromoquinolinic acid
• CAS NO: 98555-51-2
• Molecular Formula: C₇H₄BrNO₄
• Molecular Weight: 246.01
• Product Categories: Heterocycle-Pyridine series
• Mol File: 98555-51-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 165 ºC
• Boiling Point: 434.687 °C at 760 mmHg
• Flash Point: 216.691 °C
• Appearance: /
• Density: 1.985
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.13±0.10(Predicted)
• CAS DataBase Reference: DIMETHYL 5-BROMOPYRIDINE-2,3-DICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL 5-BROMOPYRIDINE-2,3-DICARBOXYLATE(98555-51-2)
• EPA Substance Registry System: DIMETHYL 5-BROMOPYRIDINE-2,3-DICARBOXYLATE(98555-51-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 98555-51-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 808, 1961 DOI: 10.1021/jo01062a039

Upstream product

• 5332-24-1 3-bromoquinoline 
• 110-19-0 2-methylpropyl acetate 
• 860758-00-5 3-bromo-6-dibromomethyl-quinoline 
• 69268-39-9 3,6-dibromoquinoline 

Downstream Products

• 1356330-71-6 5-bromo-2,3-bis(hydroxymethyl)pyridine 
• 521980-82-5 5-bromopyridine-2,3-dicarboxylic acid dimethyl ester 
• 96464-20-9 3-benzoyl-5-bromopyridine-2-carboxylic acid 
• 20986-40-7 ethyl 5-bromo-3-pyridinecarboxylate 
• 28733-43-9 5-bromonicotinamide 
• 104290-44-0 5-bromo-N,N-diethylnicotinamide 
• 112193-41-6 5-bromonicotinic acid hydrazide 
• 29681-44-5 5-bromo-3-pyridine carboxylic acid methyl ester 
• 39620-02-5 5-bromonicotinoyl chloride 
• 113118-81-3 5-bromopyridine-3-carbaldehyde 
• 98278-78-5 3-bromofuro[3,4-b]pyridine-5,7-dione 
• 20826-04-4 5-bromo-3-pyridinecarboxylic acid 

Relevant articles and documents

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Oxidation of 2- and 3-Halogenated Quinolines: An Easy Access to 5- and 6-Halogenopyridine-2,3-dicarboxylic Acids

Pyridine-2,3-dicarboxylic acids bearing an halogen in the position α or β to the nitrogen atom were synthesized by oxidation of the corresponding quinolines. Two methods, using either ozone followed by hydrogen peroxide or ruthenium tetroxide under catalytic conditions were used. Diacids 1b,c and 2a-c substituted in 6-position by a chlorine or bromine and in 5-position by a fluorine, chlorine or bromine, respectively, were isolated in yields ranging from 46-71 percent. Yields of 6-fluoro and 6- or 5-iodo diacids 1a,d and 2d did not exceed 30 percent.