98577-49-2

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 6921-34-2 benzylmagnesium chloride 
• 25108-63-8 1-methylene-1,2,3,4-tetrahydronaphthalene 
• 100-63-0 phenylhydrazine 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 

Downstream Products

• 1186664-19-6 1-benzyl-2-formyl-3,4-dihydronaphthalene 
• 129113-15-1 1a-benzyl-1,1a,6,6a-tetrahydrocyclopropindene 
• 38899-49-9 monobenzyl-1,2,3,4-tetrahydronaphthalene 
• 301852-98-2 1-benzyl-1,2,3,4-tetrahydro-naphthalene-1,2-diol 
• 301852-61-9 1-benzyl-1,2-epoxytetralin 
• 61034-42-2 1-benzyl-3,4-dihydro-1H-naphthalen-2-one 
• 85035-87-6 1-benzyl-3,4-Δ¹-tetralin 

Relevant academic research and scientific papers

Access to Diverse Oxygen Heterocycles via Oxidative Rearrangement of Benzylic Tertiary Alcohols

A facile method for the synthesis of challenging medium-sized cyclic ethers has been developed via a novel oxidative rearrangement of benzylic tertiary alcohols. The reaction provides access to cyclic acetals with diverse substitution at both C2 and the a

A mild oxidative aryl radical addition into alkenes by aerobic oxidation of arylhydrazines

A mild and practical oxyarylation of alkenes by oxidative radical addition has been developed by using aerobic oxidation of hydrazine compounds. The use of a catalytic amount of potassium ferrocyanide trihydrate (K4[Fe(CN) 6]·3 H2O) and water accelerated this radical reaction to give peroxides or alcohols from simple alkenes in good yields. The environmentally friendly and economical radical reactions were achieved at room temperature in the presence of iron catalyst, oxygen gas, and water. A method involving aniline as a radical precursor is also described. Copyright

NOVEL EFFLUX PUMP INHIBITORS

This invention relates to compounds, which are in general potentiators of antiinfeective agents and inhibitors of bacterial efflux pumps in particular. These novel compounds i.e. substituted dihydronaphtalene derivatives and tetralin derivatives and/or their salts are useful against antibiotic-resistant microbial pathogens, for treating microbial infections by reducing the extrusion of a co-administered antimicrobial agent. This invention also provides processes for the preparation of such efflux pump inhibitors and their compositions with anti infective agents and methods for treatment of microbial infections.

The photochemical rearrangement of 1,2-dihydronaphthalenes into 1,4-dihydronaphthalenes induced by amines

The synthetic usefulness of the deprotonation/protonation reaction of excited 1,2-dihydronaphthalenes into 1,4-dihydronaphthalenes induced by amines has been investigated using 13 different substituted 1,2-dihydronaphthalenes and related compounds.The yield of the rearrangement ranges from 5 to 96percent.The formation of side-products depends on the position of protons in the substrate, which can be abstracted by the amine, and on competitive photoreactions.