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99210-76-1

threo-2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 99210-76-1 Structure

  • Basic information

    1. Product Name: threo-2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoic acid
    2. Synonyms:
    3. CAS NO:99210-76-1
    4. Molecular Formula:
    5. Molecular Weight: 259.283
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 99210-76-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: threo-2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: threo-2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoic acid(99210-76-1)
    11. EPA Substance Registry System: threo-2-amino-3-hydroxy-3-(4-(methylsulfonyl)phenyl)propanoic acid(99210-76-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 99210-76-1(Hazardous Substances Data)

99210-76-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 99210-76-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,2,1 and 0 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 99210-76:
(7*9)+(6*9)+(5*2)+(4*1)+(3*0)+(2*7)+(1*6)=151
151 % 10 = 1
So 99210-76-1 is a valid CAS Registry Number.

99210-76-1Relevant articles and documents

Asymmetric Synthesis of Florfenicol by Dynamic Reductive Kinetic Resolution with Ketoreductases

Zou, Jie,Ni, Guowei,Tang, Jiawei,Yu, Jun,Jiang, Luobin,Ju, Dianwen,Zhang, Fuli,Chen, Shaoxin

, p. 5044 - 5053 (2018)

A chemoenzymatic synthesis of the veterinary antibiotic florfenicol is described. The key step involves the dynamic reductive kinetic resolution (DYRKR) of a keto ester by using a ketoreductase-02 (KRED-02) to afford the two contiguous stereocenters of the (2S,3R)-cis-1,2-amino alcohol intermediate in >99 % ee and a diastereomeric ratio (dr) of 99 %. This green biocatalysis is environmental friendly with high enantioselectivity and product yields. Two methods for the nucleophilic fluorination step involved the use of aziridines and cyclic sulfates to safely prepare fluoroamines with high regioselectivity. Additional studies have indicated that KRED-02 can also be used to afford chiral alcohol (S)-21 in good yields with high enantioselectivity. This study shows that the integration of biocatalysis into organic synthesis can be useful and provide industrial opportunities for applications of florfenicol.

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