99796-40-4Relevant academic research and scientific papers
GUANINE DERIVATIVE
-
, (2008/06/13)
Antivirally active compounds of the formula STR1 wherein A is STR2 wherein m is 1 or 2, n is 1 or 2, whereby m is 1 when n is 2 and m is 2 when n is 1, R a ' is (CH 2) p OH, NHCONH 2 or COR a ", R a " is hydrogen, hydroxy or amino, p is 1 to 4, R b ' and R b " are independently selected from hydrogen or (CH 2) p OH, with the proviso that at least one of R b ' or R b " is hydrogen; or R b ' and R b " together constitute an additional carbon-carbon bond to form an alkyne; or a physiologically acceptable salt, geometric or optical isomer thereof; pharmaceutical preparations containing the compounds and methods for treatment of virus infections.
Synthesis and Biological Activity of Unsaturated Carboacyclic Purine Nucleoside Analogues
Haines, David R.,Tseng, Christopher K. H.,Marquez, Victor E.
, p. 943 - 947 (2007/10/02)
Two new carboacyclic nucleoside analogues, 9-adenine (6) and 9-guanine (5), modeled on the unsaturated carbocyclic nucleoside analogue neplanocin A (2), have been synthesized an
