Attempt to Use a β-ketosulfone Bearing a Simple Phenyl Group in the Lewis Acid Promoted Substitution Reaction

January 05, 2024

• Title:       

  Attempt to Use a β-ketosulfone Bearing a Simple Phenyl  Group in the Lewis Acid Promoted Substitution Reaction

  Ketosulfonyl indoles in the regiodefined synthesis of tryptophols and related indole derivatives

• FigureMark:

  Scheme8

• Associated context:

  The peculiar behavior of the indole ring in deter-  mining the special reactivity of ketosulfonyl indoles 3 is further  highlighted by a test experiment carried out on the parent β-keto-  sulfone 14 in which the indole nucleus is substituted by a phenyl  ring (Scheme 8).