- tert-Butyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate
- tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-carboxylate
- tert-Butyl (2R)-2-(hydroxymethyl)-5-oxopyrrolidine-1-carboxylate
- tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
- tert-Butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate
- tert-Butyl [(1R)-1-(4-bromophenyl)ethyl]carbamate
- tert-Butyl [(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl[(4-nitrophenyl)sulfonyl]amino]propyl]carbamate
- tert-Butyl [(1S,3S)-3-[3-(3-methoxypropoxy)-4-methoxybenzyl]-1-formyl-4-methylpentyl]carbamate
- tert-butyl 1,4,5,6-tetrahydropyridine-3-carboxylate
- tert-Butyl 1,5-diazocane-1-carboxylate
- 172900-88-85-Oxazolidinepropanoic acid,3-[(1,1-dimethylethoxy)carbonyl]-4-[(2S)-2-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-3-methylbutyl]-2,2-dimethyl-|á-(1-methylethyl)-,(|áS,4S,5S)
- 172900-92-4Carbamic acid,N-[(1S,2S,4S)-2-hydroxy-1-[(2S)-2-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-3-methylbutyl]-5-methyl-4-[(phenylmethoxy)methyl]hexyl]-,1,1-dimethylethyl ester
- 172901-00-71-(((S)-2-(Bromomethyl)-3-methylbutoxy)methyl)benzene
- 1729-02-82H-1-Benzopyran-3-carboxylicacid, 8-methoxy-2-oxo-, ethyl ester
- 17293-03-7Benzene,1,3,5-trichloro-2-(chloromethyl)-
- 172932-10-4Benzaldehyde,4-[(2-chloro-6-fluorophenyl)methoxy]-
- 17293-44-62-Phenylcyclobutanamine
- 172935-91-0Benzoic acid,2,6-difluoro-, hydrazide
- 172939-50-3Quinoline,8-bromo-4-methyl-
- 172939-67-23-O-Benzoyl-N-acetyl-a-D-galactosaminyl-1-O-N-(Fmoc)serine Phenacylester
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
tert-Butyl [(1S,3S)-3-[3-(3-methoxypropoxy)-4-methoxybenzyl]-1-formyl-4-methylpentyl]carbamate |
EINECS | N/A |
| CAS No. | 172900-83-3 | Density | 1.046 g/cm3 |
| PSA | 83.09000 | LogP | 4.79840 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C24H39NO6 | Boiling Point | 554.43 °C at 760 mmHg |
| Molecular Weight | 437.577 | Flash Point | 289.109 °C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Carbamicacid, [(1S,3S)-1-formyl-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]-,1,1-dimethylethyl ester (9CI);Carbamic acid,[1-formyl-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methylpentyl]-,1,1-dimethylethyl ester, [S-(R*,R*)]-; |
Article Data | 5 |
tert-Butyl [(1S,3S)-3-[3-(3-methoxypropoxy)-4-methoxybenzyl]-1-formyl-4-methylpentyl]carbamate Synthetic route
- 172900-82-2
(2S,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexan-1-ol
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| With sulfur trioxide pyridine complex; triethylamine In dimethyl sulfoxide at 0 - 20℃; for 1h; | 100% |
| With sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine at 0 - 20℃; for 1h; | 100% |
| With oxalyl dichloride; dimethyl sulfoxide; triethylamine In dichloromethane Swern oxidation; | 89% |
- 656241-21-3
methyl (2S,4S)-2-{[(tert-butoxy)carbonyl]amino}-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexanoate
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| With diisobutylaluminium hydride In toluene at -75℃; for 0.833333h; | |
| Multi-step reaction with 2 steps 1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 2: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
- 866030-33-3
(2R,5S)-3,6-diethoxy-2-isopropyl-5-((S)-2-(4-methoxy-3-(3-methoxypropoxy)benzyl)-3-methylbutyl)-2,5-dihydropyrazine
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: HCl / acetonitrile 2: Et3N 3: NaBH4 / ethanol 4: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme |
- 621-59-0
isovanillin
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 12 steps 1: 98 percent / K2CO3 / acetonitrile 2: NaBH4 / ethanol 3: PBr3 / CH2Cl2 4: 76 percent / LiHMDS / tetrahydrofuran 5: 81 percent / LiOH; H2O2 6: 95 percent / LAH / tetrahydrofuran 7: 97 percent / PPh3; NBS / CH2Cl2 8: 68 percent / n-BuLi 9: HCl / acetonitrile 10: Et3N 11: NaBH4 / ethanol 12: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
| Multi-step reaction with 11 steps 1.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran; toluene / 24 h / 20 °C 2.1: sodium tetrahydroborate; ethanol / 20 °C 3.1: pyridine; phosphorus tribromide / diethyl ether / 3 h / 20 °C 4.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 4.2: 20 °C / Cooling with acetone-dry ice 5.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 6.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 7.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 7.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 8.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 8.2: 0 °C 9.1: dichloromethane / 14 h / 20 °C 10.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 11.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
- 145589-03-3
(R)-4-benzyl-3-(3-methylbutyryl)oxazolidin-2-one
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 9 steps 1: 76 percent / LiHMDS / tetrahydrofuran 2: 81 percent / LiOH; H2O2 3: 95 percent / LAH / tetrahydrofuran 4: 97 percent / PPh3; NBS / CH2Cl2 5: 68 percent / n-BuLi 6: HCl / acetonitrile 7: Et3N 8: NaBH4 / ethanol 9: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
| Multi-step reaction with 8 steps 1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 1.2: 20 °C / Cooling with acetone-dry ice 2.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 3.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 4.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 5.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 5.2: 0 °C 6.1: dichloromethane / 14 h / 20 °C 7.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 8.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
- 172900-75-3
4-methoxy-3-(3-methoxypropoxy)benzaldehyde
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 11 steps 1: NaBH4 / ethanol 2: PBr3 / CH2Cl2 3: 76 percent / LiHMDS / tetrahydrofuran 4: 81 percent / LiOH; H2O2 5: 95 percent / LAH / tetrahydrofuran 6: 97 percent / PPh3; NBS / CH2Cl2 7: 68 percent / n-BuLi 8: HCl / acetonitrile 9: Et3N 10: NaBH4 / ethanol 11: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
| Multi-step reaction with 10 steps 1.1: sodium tetrahydroborate; ethanol / 20 °C 2.1: pyridine; phosphorus tribromide / diethyl ether / 3 h / 20 °C 3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 3.2: 20 °C / Cooling with acetone-dry ice 4.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 5.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 6.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 6.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 7.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 7.2: 0 °C 8.1: dichloromethane / 14 h / 20 °C 9.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 10.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
- 172900-70-8
(R)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutanol
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 6 steps 1: 97 percent / PPh3; NBS / CH2Cl2 2: 68 percent / n-BuLi 3: HCl / acetonitrile 4: Et3N 5: NaBH4 / ethanol 6: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
| Multi-step reaction with 6 steps 1.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 2.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 2.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 3.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 3.2: 0 °C 4.1: dichloromethane / 14 h / 20 °C 5.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 6.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
- 172900-71-9
(R)-3-[4-methoxy-3-(3-methoxypropoxy)phenyl]-2-(1-methylethyl)propanoic acid
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 7 steps 1: 95 percent / LAH / tetrahydrofuran 2: 97 percent / PPh3; NBS / CH2Cl2 3: 68 percent / n-BuLi 4: HCl / acetonitrile 5: Et3N 6: NaBH4 / ethanol 7: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme |
- 172900-73-1
4-(bromomethyl)-1-methoxy-2-(3-methoxypropoxy)-benzene
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 9 steps 1: 76 percent / LiHMDS / tetrahydrofuran 2: 81 percent / LiOH; H2O2 3: 95 percent / LAH / tetrahydrofuran 4: 97 percent / PPh3; NBS / CH2Cl2 5: 68 percent / n-BuLi 6: HCl / acetonitrile 7: Et3N 8: NaBH4 / ethanol 9: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
| Multi-step reaction with 8 steps 1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 1.2: 20 °C / Cooling with acetone-dry ice 2.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 3.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 4.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 5.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 5.2: 0 °C 6.1: dichloromethane / 14 h / 20 °C 7.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 8.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
- 172900-74-2
[4-methoxy-3-(3-methoxypropoxy)-phenyl]methanol
- 172900-83-3
(1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester
| Conditions | Yield |
|---|---|
| Multi-step reaction with 10 steps 1: PBr3 / CH2Cl2 2: 76 percent / LiHMDS / tetrahydrofuran 3: 81 percent / LiOH; H2O2 4: 95 percent / LAH / tetrahydrofuran 5: 97 percent / PPh3; NBS / CH2Cl2 6: 68 percent / n-BuLi 7: HCl / acetonitrile 8: Et3N 9: NaBH4 / ethanol 10: 89 percent / DMSO; ClC(O)C(O)Cl; Et3N / CH2Cl2 View Scheme | |
| Multi-step reaction with 9 steps 1.1: pyridine; phosphorus tribromide / diethyl ether / 3 h / 20 °C 2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / Cooling with acetone-dry ice 2.2: 20 °C / Cooling with acetone-dry ice 3.1: lithium borohydride; water / diethyl ether / 0.67 h / 0 °C 4.1: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h 5.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / Cooling with acetone-dry ice 5.2: 16.17 h / -78 °C / Cooling with acetone-dry ice 6.1: hydrogenchloride; water / acetonitrile / 3 h / 20 °C 6.2: 0 °C 7.1: dichloromethane / 14 h / 20 °C 8.1: lithium borohydride / tetrahydrofuran / 15 h / 20 °C 9.1: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / 1 h / 0 - 20 °C View Scheme |
tert-Butyl [(1S,3S)-3-[3-(3-methoxypropoxy)-4-methoxybenzyl]-1-formyl-4-methylpentyl]carbamate Chemical Properties
Product Name: tert-Butyl [(1S,3S)-3-[3-(3-methoxypropoxy)-4-methoxybenzyl]-1-formyl-4-methylpentyl]carbamate (CAS NO.172900-83-3)
Molecular Formula: C24H39NO6
Molecular Weight: 437.57g/mol
Mol File: 172900-83-3.mol
Boiling point: 554.43 °C at 760 mmHg
Flash Point: 289.109 °C
Density: 1.046 g/cm3
Surface Tension: 35.657 dyne/cm
Enthalpy of Vaporization: 83.55 kJ/mol
tert-Butyl [(1S,3S)-3-[3-(3-methoxypropoxy)-4-methoxybenzyl]-1-formyl-4-methylpentyl]carbamate Specification
tert-Butyl [(1S,3S)-3-[3-(3-methoxypropoxy)-4-methoxybenzyl]-1-formyl-4-methylpentyl]carbamate , its CAS NO. is 172900-83-3, the synonyms are Aliskiren inter-8 ; (1S,3S)-{1-formyl-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid tert-butyl ester .
What can I do for you?
Get Best Price
